Management of Coronavirus Disease 2019 (COVID-19) Pandemic: From Diagnosis to Treatment Strategies

被引:2
作者
Hadisi, Zhina [1 ]
Walsh, Tavia [1 ]
Dabiri, Seyed Mohammad Hossein [1 ]
Seyfoori, Amir [1 ]
Hamdi, David [1 ]
Mirani, Bahram [2 ,3 ,4 ]
Pagan, Erik [1 ]
Jardim, Armando [1 ]
Akbari, Mohsen [1 ,5 ,6 ]
机构
[1] Univ Victoria, Dept Mech Engn, Lab Innovat Microengn LiME, Ctr Biomed Res, 3800 Finnerty Rd, Victoria, BC V8P 2C5, Canada
[2] Univ Toronto, Dept Mech & Ind Engn, Toronto, ON M5S 3G8, Canada
[3] Univ Toronto, Inst Biomat & Biomed Engn IBBME, Toronto, ON M5S 3G9, Canada
[4] Univ Toronto, Ted Rogers Ctr Heart Res, Inst Biomed Engn BME, Toronto, ON M5G 1M1, Canada
[5] Univ Victoria, Ctr Biomed Res, 3800 Finnerty Rd, Victoria, BC V8P 2C5, Canada
[6] Univ Victoria, Ctr Adv Mat & Related Technol CAMTEC, 3800 Finnerty Rd, Victoria, BC V8P 2C5, Canada
关键词
coronavirus disease 2019; COVID; 19; MERS; SARS; treatment strategies; RESPIRATORY SYNDROME CORONAVIRUS; CONVALESCENT PLASMA THERAPY; CRITICALLY-ILL PATIENTS; TO-HUMAN TRANSMISSION; MERS-COV INFECTION; SYNDROME SARS; CHEST CT; CLINICAL CHARACTERISTICS; CORTICOSTEROID-THERAPY; PROTECTIVE IMMUNITY;
D O I
10.1002/adtp.202000173
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Following the emergence of severe acute respiratory syndrome (SARS) in 2002 and the Middle East respiratory syndrome (MERS) in 2012, the world is now combating a third large-scale outbreak caused by a coronavirus, the coronavirus disease 2019 (COVID-19). After the rapid spread of SARS-coronavirus (CoV)-2 (the virus causing COVID-19) from its origin in China, the World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC) on January 30, 2020. From the beginning of the COVID-19 pandemic, a significant number of studies have been conducted to better understand the biology and pathogenesis of the novel coronavirus, and to aid in developing effective treatment regimens, therapeutics, and vaccines. This review focuses on the recent advancements in the rapidly evolving areas of clinical care and management of COVID-19. The emerging strategies for the diagnosis and treatment of this disease are explored, and the development of effective vaccines is reviewed.
引用
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页数:21
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