Contribution of 18fluoro-deoxyglucose PET/CT for the diagnosis of infectious diseases

被引：16
作者：
Revest, M. [1 ,2 ]
Patrat-Delon, S. [1 ]
Devillers, A. [3 ]
Tattevin, P. [1 ,2 ,4 ]
Michelet, C. [1 ,2 ]
机构：
[1] CHU Rennes, Serv Malad Infect & Reanim Med, F-35033 Rennes 9, France
[2] Univ Rennes 1, CHU Rennes, CIC Inserm 0203, F-35033 Rennes 9, France
[3] Ctr Reg Lutte Canc Eugene Marquis, Nucl Med Serv, F-35042 Rennes, France
[4] Univ Rennes 1, Inserm U835, F-35043 Rennes, France
来源：
MEDECINE ET MALADIES INFECTIEUSES | 2014年 / 44卷 / 06期
关键词：
(18)FDG-PET/CT; Fever of unknown origin; Infective endocarditis; Vascular prosthesis infection; Osteomyelitis; POSITRON-EMISSION-TOMOGRAPHY; CLINICAL-PRACTICE GUIDELINES; GRAM-POSITIVE BACTEREMIA; F-18 FDG PET; UNKNOWN ORIGIN; CHRONIC OSTEOMYELITIS; PERIPROSTHETIC INFECTION; PROSPECTIVE MULTICENTER; STAPHYLOCOCCUS-AUREUS; PROMISING ROLE;
D O I：
10.1016/j.medmal.2014.04.007
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The diagnosis of some infectious diseases is sometimes difficult to make and new diagnostic tools have been regularly assessed to that end. (18)fluoro-deoxyglucose ((18)FDG) positron-emission tomography (PET) coupled with computed tomography (CT) is one of these new procedures. It has been evaluated for numerous infectious diseases with uneven results. A literature review allowed drawing some conclusions. First, (18)FDG-PET/CT is not currently a first-line procedure for infectious diseases. Second, it has proved useful for the evaluation of patients presenting with fever of unknown origin (FUO). Its negative predictive value is 100%: the symptoms of patients experiencing FUO with negative first-line investigations and a negative (18)FDG-PET/CT will almost always spontaneously disappear. Third, (18)FDG-PET/CT also seems to be contributive for the diagnosis of vascular prosthesis infections or osteomyelitis. Fourth, it has promising results for patients presenting with infective endocarditis, especially for secondary infectious foci, or for patients presenting with suspected infection of pacemakers or implanted defibrillator; but results are still preliminary and must be confirmed. Finally (18)FDG-PET/CT cannot be recommended yet for other infectious diseases due to lack of published data. (C) 2014 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：251 / 260
页数：10
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