A cyanide selective off-on fluorescent chemosensor with in vivo imaging in 100% water: solid probe preferred over in situ generation

被引：26

作者：

Das, Sanju ^{[1
,2
]}

Biswas, Surajit ^{[1
]}

Mukherjee, Santanu ^{[3
]}

Bandyopadhyay, Jaya ^{[3
]}

Samanta, Subhodip ^{[2
]}

Bhowmick, Indrani ^{[4
]}

Hazra, Dipak Kumar ^{[5
]}

Ray, Ambarish ^{[2
]}

Parui, Partha Pratim ^{[1
]}

机构：

[1] Jadavpur Univ, Dept Chem, Kolkata 700032, India

[2] Maulana Azad Coll, Dept Chem, Kolakta 700013, India

[3] West Bengal Univ Technol, Dept Biotechnol, Kolkata 700064, India

[4] Univ Delhi, Dept Chem, Delhi 110007, India

[5] Indian Assoc Cultivat Sci, Dept Solid State Phys, Kolkata 700032, India

来源：

RSC ADVANCES | 2014年 / 4卷 / 19期

关键词：

Fluorescence - Physiology - Physiological models - Synthesis (chemical);

D O I：

10.1039/c4ra00069b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A nontoxic fluorescent chemosensor [Cu(BP)HMB](2)(ClO4)(2) (1) synthesized in solid phase, exhibits unprecedented selectivity and sensitivity over the allied in situ complexes to perform fluorescence in "turn-off-on" mode for sensing cyanide in 100% aqueous medium under physiological conditions and for in vivo imaging using the nematode C. elegans. Below mu M detection limit, instantaneous and excellent ratiometric responses are also beneficial to detect trace amounts of anthropogenic or biogenic cyanide.

引用

页码：9656 / 9659

页数：4

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