Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: a genomic perspective

被引:39
|
作者
Jebanathirajah, JA [1 ]
Peri, S
Pandey, A
机构
[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
[2] Johns Hopkins Univ, McKusick Nathans Inst Genet Med, Baltimore, MD 21287 USA
关键词
D O I
10.1016/S1360-1385(02)02309-9
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.
引用
收藏
页码:388 / 391
页数:4
相关论文
共 50 条
  • [41] Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpB
    Kaplan-Tuerkoez, Burcu
    Koelblen, Thomas
    Felix, Christine
    Candusso, Marie-Pierre
    O'Callaghan, David
    Vergunst, Annette C.
    Terradot, Laurent
    FEBS LETTERS, 2013, 587 (21) : 3412 - 3416
  • [42] The axon degeneration gene SARM1 is evolutionarily distinct from other TIR domain-containing proteins
    Malapati, Harsha
    Millen, Spencer M.
    Buchser, William J.
    MOLECULAR GENETICS AND GENOMICS, 2017, 292 (04) : 909 - 922
  • [43] TIR Domain-Containing Protein SARM1 Diversity in Deuterostomes and Lophotrochozoans
    Briseno, J. L.
    Tassia, M. G.
    Waits, D. S.
    Halanych, K. M.
    INTEGRATIVE AND COMPARATIVE BIOLOGY, 2020, 60 : E287 - E287
  • [44] Homo-oligomerization is essential for toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-κB and interferon regulatory factor-3 activation
    Funami, Kenji
    Sasai, Miwa
    Oshiumi, Hiroyuki
    Seya, Tsukasa
    Matsumoto, Misako
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (26) : 18283 - 18291
  • [45] Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature
    Demont, Heloise
    Rembliere, Celine
    Culerrier, Raphael
    Sauvaget, Madeline
    Deslandes, Laurent
    Bernoux, Maud
    CELL REPORTS, 2025, 44 (03):
  • [46] FUN14 domain-containing 1-mediated mitophagy suppresses interleukin-1β production in macrophages
    Huang, Jia
    Zhu, Tengfei
    Rong, Rong
    You, Mengling
    Ji, Dan
    Li, Haibo
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 88
  • [47] Functional diversity of Toll/interleukin-1 receptor domains in flowering plants and its translational potential
    Ogden, Sam C.
    Nishimura, Marc T.
    Lapin, Dmitry
    CURRENT OPINION IN PLANT BIOLOGY, 2023, 76
  • [48] Variation in plant Toll/Interleukin-1 receptor domain protein dependence on ENHANCED DISEASE SUSCEPTIBILITY 1
    Johanndrees, Oliver
    Baggs, Erin L.
    Uhlmann, Charles
    Locci, Federica
    Laessle, Henriette L.
    Melkonian, Katharina
    Kaeufer, Kiara
    Dongus, Joram A.
    Nakagami, Hirofumi
    Krasileva, Ksenia, V
    Parker, Jane E.
    Lapin, Dmitry
    PLANT PHYSIOLOGY, 2023, 191 (01) : 626 - 642
  • [49] Determining the role of TIR domain of Interleukin-1 receptor 8 (SIGIRR) in regulating TLR4 signalling
    Nimma, Surekha
    Nanson, Jeffrey
    Ve, Thomas
    Kobe, Bostjan
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2021, 77 : C785 - C785
  • [50] Therapeutic effect of Qinghuayin(清化饮)against chronic atrophic gastritis through the inhibition of toll or interleukin-1 receptor domain-containing adaptor inducing interferon-βsignaling pathway
    HE Youcheng
    YAO Xiaoling
    LI Sihan
    ZHOU Hongjian
    XU Ruoying
    ZHENG Rong
    XIAO Wendi
    SU Ning
    LIN Ping
    HUANG Minghan
    JournalofTraditionalChineseMedicine, 2022, 42 (02) : 221 - 226