Toll and interleukin-1 receptor (TIR) domain-containing proteins in plants: a genomic perspective

被引：39
|
作者：
Jebanathirajah, JA [1 ]
Peri, S
Pandey, A
机构：
[1] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA
[2] Johns Hopkins Univ, McKusick Nathans Inst Genet Med, Baltimore, MD 21287 USA
来源：
TRENDS IN PLANT SCIENCE | 2002年 / 7卷 / 09期
关键词：
D O I：
10.1016/S1360-1385(02)02309-9
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Toll and interleukin-1 receptor (TIR) domains were originally described from comparisons of proteins found in mammals and Drosophila. They are now known to occur in several organisms, with the most TIR proteins being found in Arabidopsis: our analysis of the sequenced Arabidopsis genome has revealed the presence of at least 135 proteins containing TIR domains. Several novel types of TIR-domain-containing proteins are found in Arabidopsis that are not found in other genomes. Here, we discuss the roles of TIR-domain-containing proteins in pathogen resistance and as candidate signaling modules.
引用
收藏
页码：388 / 391
页数：4
相关论文
共 50 条
  • [31] Comparative Analysis of SWIRM Domain-Containing Proteins in Plants
    Gao, Yan
    Yang, Songguang
    Yuan, Lianyu
    Cui, Yuhai
    Wu, Keqiang
    COMPARATIVE AND FUNCTIONAL GENOMICS, 2012,
  • [32] Genetic analysis of Toll/Interleukin-1 Receptor (TIR) domain sequences from rhesus macaque Toll-like receptors (TLRs) 1–10 reveals high homology to human TLR/TIR sequences
    Sonali K. Sanghavi
    Raj Shankarappa
    Todd A. Reinhart
    Immunogenetics, 2004, 56 : 667 - 674
  • [33] The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence
    O'Neill, L
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2000, 28 : 557 - 563
  • [34] Genetic analysis of Toll/Interleukin-1 Receptor (TIR) domain sequences from rhesus macaque Toll-like receptors (TLRs) 1-10 reveals high homology to human TLR/TIR sequences
    Sanghavi, SK
    Shankarappa, R
    Reinhart, TA
    IMMUNOGENETICS, 2004, 56 (09) : 667 - 674
  • [35] Therapeutic effect of Qinghuayin () against chronic atrophic gastritis through the inhibition of toll or interleukin-1 receptor domain-containing adaptor inducing interferon-β signaling pathway
    He Youcheng
    Yao Xiaoling
    Li Sihan
    Zhou Hongjian
    Xu Ruoying
    Zheng Rong
    Xiao Wendi
    Su Ning
    Lin Ping
    Huang Minghan
    JOURNAL OF TRADITIONAL CHINESE MEDICINE, 2022, 42 (02) : 221 - 226
  • [36] Toll/Interleukin-1 Receptor Domain Dimers as the Platform for Activation and Enhanced Inhibition of Toll-like Receptor Signaling
    Fekonja, Ota
    Bencina, Mojca
    Jerala, Roman
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (37) : 30993 - 31002
  • [37] Decapping NAD-RNAs: TIR domain-containing proteins stand out for specificity
    Cao, Dechang
    TRENDS IN BIOCHEMICAL SCIENCES, 2024, 49 (06) : 477 - 479
  • [38] TIR8/SIGIRR is an interleukin-1 receptor/toll like receptor family member with regulatory functions in inflammation and immunity
    Riva, Federica
    Bonavita, Eduardo
    Barbati, Elisa
    Muzio, Marta
    Mantovani, Alberto
    Garlanda, Cecilia
    FRONTIERS IN IMMUNOLOGY, 2012, 3
  • [39] Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL
    Khan, JA
    Brint, EK
    O'Neill, LAJ
    Tong, L
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (30) : 31664 - 31670
  • [40] The axon degeneration gene SARM1 is evolutionarily distinct from other TIR domain-containing proteins
    Harsha Malapati
    Spencer M. Millen
    William J. Buchser
    Molecular Genetics and Genomics, 2017, 292 : 909 - 922
12345