Synthesis and antitumor activity of 4β-(1,2,3-triazol-1-yl) podophyllotoxins

被引：0
作者：
Cao, CN
Chen, YY
Wang, YG
Chen, YZ
机构：
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
[2] Qinghai Univ, Dept Appl Chem, Xining 810000, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 1999年 / 10卷 / 12期
关键词：
podophyllotoxin; antitumor; synthesis;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three 4 beta-(1,2,3-triazol-1-yl) podophyllotoxins 2 similar to 4 have been synthesized and tested for their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than the clinically used etoposide (VP-16) against L1210 cells.
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收藏
页码：1003 / 1006
页数：4
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