Alexithymia in PTSD psychometric and FMRI studies

被引：56

作者：

Frewen, Paul A.

Pain, Claire

Dozois, David J. A.

Lanius, Ruth A.

机构：

[1] Univ Western Ontario, Dept Psychol, London, ON N6A SAS, Canada

[2] Univ Western Ontario, Dept Psychiat, London, ON N6A SAS, Canada

[3] Univ Western Ontario, Dept Neurosci, London, ON N6A SAS, Canada

来源：

PSYCHOBIOLOGY OF POSTTRAUMATIC STRESS DISORDER: A DECADE OF PROGRESS | 2006年 / 1071卷

关键词：

alexithymia; posttraumatic stress disorder; dissociation; child abuse; child neglect; fMRI;

D O I：

10.1196/annals.1364.029

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Two studies examined correlates of alexithymia in posttraumatic stress disorder (PTSD). In study 1 (n = 77 individuals with PTSD and 45 controls) Toronto alexithymia scale (TAS-20) scores were positively correlated with PTSD symptoms, dissociation, and childhood abuse and neglect. In study 2, TAS-20 scores were examined as correlates of functional magnetic resonance imaging (MRI) blood oxygen level dependent (BOLD) response to trauma script imagery. In 16 controls, TAS-20 scores correlated positively with response in medial prefrontal cortex (mPFC), and negatively with response in anterior cingulate cortex (ACC) and thalamus. In 26 individuals with PTSD, TAS-20 scores correlated positively with response in insula, posterior cingulate cortex (PCC), and thalamus, and negatively with response in ACC.

引用

页码：397 / 400

页数：4

共 8 条

[1] Effect of impaired recognition and expression of emotions on frontocingulate cortices: An fMRI study of men with alexithymia [J].