Low Levels of Antiretroviral-Resistant HIV Infection in a Routine Clinic in Cameroon that Uses the World Health Organization (WHO) Public Health Approach to Monitor Antiretroviral Treatment and Adequacy with the WHO Recommendation for Second-Line Treatment

被引:54
作者
Kouanfack, Charles [3 ]
Montavon, Celine [1 ]
Laurent, Christian [1 ]
Aghokeng, Avelin [2 ]
Kenfack, Alain [3 ]
Bourgeois, Anke [4 ]
Koulla-Shiro, Sinata [3 ]
Mpoudi-Ngole, Eitel [2 ]
Peeters, Martine [1 ]
Delaporte, Eric [1 ,4 ]
机构
[1] Univ Montpellier 1, Inst Rech Dev, UMR 145, F-34394 Montpellier 5, France
[2] IRD, Inst Rech Med & Plantes Med IMPM, CRESAR, Virol Lab, Yaounde, Cameroon
[3] Cent Hosp, Yaounde, Cameroon
[4] CHU Montpellier, Ensemble Solidar Therapeut Hosp Reseau Project, Montpellier, France
关键词
THERAPY;
D O I
10.1086/597779
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A cross-sectional study, performed at a routine human immunodeficiency virus (HIV)/AIDS clinic in Cameroon that uses the World Health Organization public health approach, showed low rates of virological failure and drug resistance at 12 and 24 months after initiation of antiretroviral therapy. Importantly, the cross-sectional study also showed that the World Health Organization recommendation for second-line treatment would be effective in almost all patients with HIV drug resistance mutations.
引用
收藏
页码:1318 / 1322
页数:5
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