Childhood obesity in specialist care - searching for a healthy obese child

被引:13
作者
Dalla Valle, Marketta [1 ,2 ]
Laatikainen, Tiina [3 ,4 ,5 ]
Kalliokoski, Tomi [6 ]
Nykanen, Paivi [7 ]
Jaaskelainen, Jarmo [2 ,8 ]
机构
[1] North Karelia Cent Hosp, Dept Pediat, Joensuu, Finland
[2] Univ Eastern Finland, Dept Pediat, Kuopio, Finland
[3] Univ Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland
[4] Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland
[5] North Karelia Hosp Dist, Joensuu, Finland
[6] Univ Eastern Finland, Sch Med, Kuopio, Finland
[7] Mikkeli Cent Hosp, Dept Pediat, Mikkeli, Finland
[8] Kuopio Univ Hosp, Dept Pediat, SF-70210 Kuopio, Finland
关键词
Adolescent; blood glucose; blood pressure; child; dyslipidemias; fatty liver; hyperinsulinism; metabolism; obesity; CARDIOVASCULAR RISK-FACTORS; BODY-MASS INDEX; FATTY LIVER-DISEASE; BLOOD-PRESSURE; OVERWEIGHT CHILDREN; INSULIN-RESISTANCE; PUBERTAL CHANGES; UNITED-STATES; ADOLESCENTS; ADULTHOOD;
D O I
10.3109/07853890.2015.1083118
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction One in three obese adults is classified as metabolically healthy, but there is less evidence in obese children. We studied the overall clinical presentation of Finnish obese children and the prevalence of cardiometabolic risk factors with child-specific cut-offs. Material and methods This is a cross-sectional register-based study of 2-18-year-old children (n = 900) evaluated for obesity in three hospitals in 2005-2012. Clinical and metabolic data were related to sex, age, puberty, and obesity grade and analyzed using chi-square and non-parametric tests. Results In 80% of cases at least one cardiovascular risk factor was present. Only 3% of subjects for whom complete metabolic data were available (n = 360) had no metabolic disorder. Systolic blood pressure was hypertensive in 50.2% and diastolic in 14.5% of the children. The youngest children had highest body mass index SD score. Obesity was more severe in boys than girls (p < 0.001). Hypertensive systolic blood pressure values (p = 0.012), prediabetes (p < 0.001), fatty liver (p < 0.001), and dyslipidemia (p = 0.025) were more prevalent in 15-18-year-old boys than girls. Conclusion Most obese children in specialist care have cardiovascular risk factors; this indicates that earlier intervention is needed.
引用
收藏
页码:639 / 654
页数:16
相关论文
共 59 条
[1]   Pediatric Nonalcoholic Fatty Liver Disease in 2009 [J].
Alisi, Anna ;
Manco, Melania ;
Vania, Andrea ;
Nobili, Valerio .
JOURNAL OF PEDIATRICS, 2009, 155 (04) :469-474
[2]   Childhood body-mass index and the risk of coronary heart disease in adulthood [J].
Baker, Jennifer L. ;
Olsen, Lina W. ;
Sorensen, Thorkild I. A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (23) :2329-2337
[3]   Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults [J].
Berenson, GS ;
Srinivasan, SR ;
Bao, WH ;
Newman, WP ;
Tracy, RE ;
Wattigney, WA .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (23) :1650-1656
[4]   Higher Prevalence of Obesity Among Children With Asthma [J].
Black, Mary Helen ;
Smith, Ning ;
Porter, Amy H. ;
Jacobsen, Steven J. ;
Koebnick, Corinna .
OBESITY, 2012, 20 (05) :1041-1047
[5]   Metabolically healthy obesity from childhood to adulthood - Does weight status alone matter? [J].
Blueher, Susann ;
Schwarz, Peter .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2014, 63 (09) :1084-1092
[6]   Metabolically Healthy Obesity-Does it Exist? [J].
Boonchaya-Anant, Patchaya ;
Apovian, Caroline M. .
CURRENT ATHEROSCLEROSIS REPORTS, 2014, 16 (10)
[7]   Glucose tolerance status in 510 children and adolescents attending an obesity clinic in Central Italy [J].
Brufani, Claudia ;
Ciampalini, Paolo ;
Grossi, Armando ;
Fiori, Rossana ;
Fintini, Danilo ;
Tozzi, Alberto ;
Cappa, Marco ;
Barbetti, Fabrizio .
PEDIATRIC DIABETES, 2010, 11 (01) :47-54
[8]   Tracking of blood pressure from childhood to adulthood - A systematic review and meta-regression analysis [J].
Chen, Xiaoli ;
Wang, Youfa .
CIRCULATION, 2008, 117 (25) :3171-3180
[9]   Establishing a standard definition for child overweight and obesity worldwide: international survey [J].
Cole, TJ ;
Bellizzi, MC ;
Flegal, KM ;
Dietz, WH .
BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7244) :1240-1243
[10]   Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents [J].
Correll, Christoph U. ;
Manu, Peter ;
Olshanskiy, Vladimir ;
Napolitano, Barbara ;
Kane, John M. ;
Malhotra, Anil K. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (16) :1765-1773