Activation of the hTAS2R14 Human Bitter-Taste Receptor by (-)-Epigallocatechin Gal late and (-)-Epicatechin Gal late

被引：32

作者：

Yamazaki, Toyomi ^{[1
]}

Narukawa, Masataka ^{[2
]}

Mochizuki, Mineko ^{[1
]}

Misaka, Takumi ^{[2
]}

Watanabe, Tatsuo ^{[1
]}

机构：

[1] Univ Shizuoka, Grad Div Nutr & Environm Sci, Suruga Ku, Shizuoka 4228526, Japan

[2] Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2013年 / 77卷 / 09期

关键词：

green tea; catechin; bitter taste; bitter taste receptor; hTAS2R14; GREEN TEA CATECHINS; BLACK TEA; MICE; FAMILY; CELLS;

D O I：

10.1271/bbb.130329

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tea catechins have strong bitterness and influence the taste of tea. Among the 25 human bitter-taste receptors (TAS2Rs), we found that hTAS2R14 responded to catechins, in addition to hTAS2R39, a known catechin receptor. Although hTAS2R14 responded to (-)-epicatechin gallate and (-)-epigallocatechin gallate, it did not respond to (-)-epicatechin and (-)-epigallocatechin.

引用

页码：1981 / 1983

页数：3

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