Is it time to change our vision of tumor metabolism prior to immunotherapy?

被引:49
作者
Grizzi, Fabio [1 ]
Castello, Angelo [2 ]
Lopci, Egesta [2 ]
机构
[1] Humanitas Clin & Res Hosp, Dept Immunol & Inflammat, Milan, Italy
[2] Humanitas Clin & Res Hosp, Nucl Med, Via Manzoni 56, I-20089 Rozzano, MI, Italy
关键词
CELL LUNG-CANCER; EXPRESSION; BLOCKADE; PET/CT; EZH2;
D O I
10.1007/s00259-018-3988-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
引用
收藏
页码:1072 / 1075
页数:4
相关论文
共 10 条
[1]   Increased Levels of Tumor-Infiltrating Lymphocytes are Associated with Improved Recurrence-Free Survival in Stage 1A Non-Small-Cell Lung Cancer [J].
Horne, Zachary D. ;
Jack, Robert ;
Gray, Zachary T. ;
Siegfried, Jill M. ;
Wilson, David O. ;
Yousem, Samuel A. ;
Nason, Katie S. ;
Landreneau, Rodney J. ;
Luketich, James D. ;
Schuchert, Matthew J. .
JOURNAL OF SURGICAL RESEARCH, 2011, 171 (01) :1-5
[2]  
Liu J, PLOS ONE, V11
[3]   Tumor metabolism and prognostic role of EZH2 in non-small cell lung cancer [J].
Lopci, Egesta ;
Rossi, Sabrina .
TRANSLATIONAL CANCER RESEARCH, 2017, 6 :S982-S988
[4]   Early and delayed evaluation of solid tumours with 64Cu-ATSM PET/CT: a pilot study on semiquantitative and computer-aided fractal geometry analysis [J].
Lopci, Egesta ;
Grizzi, Fabio ;
Russo, Carlo ;
Toschi, Luca ;
Grassi, Ilaria ;
Cicoria, Gianfranco ;
Lodi, Filippo ;
Mattioli, Sandro ;
Fanti, Stefano .
NUCLEAR MEDICINE COMMUNICATIONS, 2017, 38 (04) :340-346
[5]   Correlation of metabolic information on FDG-PET with tissue expression of immune markers in patients with non-small cell lung cancer (NSCLC) who are candidates for upfront surgery [J].
Lopci, Egesta ;
Toschi, Luca ;
Grizzi, Fabio ;
Rahal, Daoud ;
Olivari, Laura ;
Castino, Giovanni Francesco ;
Marchetti, Silvia ;
Cortese, Nina ;
Qehajaj, Dorina ;
Pistillo, Daniela ;
Alloisio, Marco ;
Roncalli, Massimo ;
Allavena, Paola ;
Santoro, Armando ;
Marchesi, Federica ;
Chiti, Arturo .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2016, 43 (11) :1954-1961
[6]   The Warburg effect then and now: From cancer to inflammatory diseases [J].
Palsson-McDermott, Eva M. ;
O'Neill, Luke A. J. .
BIOESSAYS, 2013, 35 (11) :965-973
[7]   Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells [J].
Rashidian, Mohammad ;
Ingram, Jessica R. ;
Dougan, Michael ;
Dongre, Anushka ;
Whang, Katherine A. ;
LeGall, Camille ;
Cragnolini, Juan J. ;
Bierie, Brian ;
Gostissa, Monica ;
Gorman, James ;
Grotenbreg, Gijsbert M. ;
Bhan, Atul ;
Weinberg, Robert A. ;
Ploegh, Hidde L. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 214 (08) :2243-2255
[8]   Metabolic characteristics of programmed cell death-ligand 1-expressing lung cancer on 18F-fluorodeoxyglucose positron emission tomography/computed tomography [J].
Takada, Kazuki ;
Toyokawa, Gouji ;
Okamoto, Tatsuro ;
Baba, Shingo ;
Kozuma, Yuka ;
Matsubara, Taichi ;
Haratake, Naoki ;
Akamine, Takaki ;
Takamori, Shinkichi ;
Katsura, Masakazu ;
Shoji, Fumihiro ;
Honda, Hiroshi ;
Oda, Yoshinao ;
Maehara, Yoshihiko .
CANCER MEDICINE, 2017, 6 (11) :2552-2561
[9]   Elevated Metabolic Activity on 18F-FDG PET/CT Is Associated with the Expression of EZH2 in Non-small Cell Lung Cancer [J].
Toyokawa, Gouji ;
Takada, Kazuki ;
Okamoto, Tatsuro ;
Kozuma, Yuka ;
Matsubara, Taichi ;
Haratake, Naoki ;
Akamine, Takaki ;
Takamori, Shinkichi ;
Katsura, Masakazu ;
Shoji, Fumihiro ;
Hamamoto, Ryuji ;
Oda, Yoshinao ;
Maehara, Yoshihiko .
ANTICANCER RESEARCH, 2017, 37 (03) :1393-1401
[10]   PD-1 blockade induces responses by inhibiting adaptive immune resistance [J].
Tumeh, Paul C. ;
Harview, Christina L. ;
Yearley, Jennifer H. ;
Shintaku, I. Peter ;
Taylor, Emma J. M. ;
Robert, Lidia ;
Chmielowski, Bartosz ;
Spasic, Marko ;
Henry, Gina ;
Ciobanu, Voicu ;
West, Alisha N. ;
Carmona, Manuel ;
Kivork, Christine ;
Seja, Elizabeth ;
Cherry, Grace ;
Gutierrez, Antonio J. ;
Grogan, Tristan R. ;
Mateus, Christine ;
Tomasic, Gorana ;
Glaspy, John A. ;
Emerson, Ryan O. ;
Robins, Harlan ;
Pierce, Robert H. ;
Elashoff, David A. ;
Robert, Caroline ;
Ribas, Antoni .
NATURE, 2014, 515 (7528) :568-+