Efficacy of Silver Diamine Fluoride for Arresting Caries Treatment

被引：188

作者：

Yee, R. ^{[1
,4
]}

Holmgren, C. ^{[1
]}

Mulder, J. ^{[1
]}

Lama, D. ^{[2
]}

Walker, D. ^{[3
]}

Helderman, W. van Palenstein ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Med Ctr, Coll Dent Sci, Dept Global Oral Hlth, NL-6500 HB Nijmegen, Netherlands

[2] United Mission Nepal Oral Hlth Programme, Kathmandu, Nepal

[3] Univ Sydney, Fac Dent, Westmead, NSW 2145, Australia

[4] NUHS, Fac Dent, Dept Prevent Dent, Singapore 119074, Singapore

来源：

JOURNAL OF DENTAL RESEARCH | 2009年 / 88卷 / 07期

关键词：

fluorides; silver diamine fluoride; clinical trial; arresting caries treatment; DENTIN; MOLARS;

D O I：

10.1177/0022034509338671

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Arresting Caries Treatment (ACT) has been proposed to manage untreated dental caries in children. This prospective randomized clinical trial investigated the caries-arresting effectiveness of a single spot application of: (1) 38% silver diamine fluoride (SDF) with tannic acid as a reducing agent; (2) 38% SDF alone; (3) 12% SDF alone; and (4) no SDF application in primary teeth of 976 Nepalese schoolchildren. The a priori null hypothesis was that the different treatments have no effect in arresting active cavitated caries. Only the single application of 38% SDF with or without tannic acid was effective in arresting caries after 6 months (4.5 and 4.2 mean number of arrested surfaces; p < 0.001), after 1 year (4.1 and 3.4; p < 0.001), and after 2 years (2.2 and 2.1; p < 0.01). Tannic acid conferred no additional benefit. ACT with 38% SDF provides an alternative when restorative treatment for primary teeth is not an option.

引用

页码：644 / 647

页数：4

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