Promoter variation in the catechol-O-methyltransferase gene is associated with remission of symptoms during fluvoxamine treatment for major depression

被引：5
作者：
Fukui, Naoki [1 ]
Suzuki, Yutaro [1 ]
Sugai, Takuro [1 ]
Watanabe, Junzo [1 ]
Ono, Shin [1 ]
Tsuneyama, Nobuto [1 ]
Someya, Toshiyuki [1 ]
机构：
[1] Niigata Univ, Dept Psychiat, Grad Sch Med & Dent Sci, Niigata, Japan
来源：
PSYCHIATRY RESEARCH | 2014年 / 218卷 / 03期
关键词：
COMT; Depression; Fluvoxamine; VAL(108/158)MET POLYMORPHISM; TREATMENT RESPONSE; PAROXETINE; SEVERITY; PLACEBO; COMT;
D O I：
10.1016/j.psychres.2014.04.030
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
We investigated the association between remission of depressive symptoms in fluvoxamine treatment and catechol-O-methyltransferase (COMT) gene. Sixteen SNPs in the COMT gene were investigated in 123 outpatients with major depression. Three single nucleotide polymorphisms located in the 5' region were associated with remission in fluvoxamine-treated outpatients with moderate to severe depression. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：353 / 355
页数：3
相关论文
共 40 条
  • [21] Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents
    DeYoung, Colin G.
    Getchell, Marya
    Koposov, Roman A.
    Yrigollen, Carolyn M.
    Haeffel, Gerald J.
    af Klinteberg, Britt
    Oreland, Lars
    Ruchkin, Vladislav V.
    Pakstis, Andrew J.
    Grigorenko, Elena L.
    PSYCHIATRIC GENETICS, 2010, 20 (01) : 20 - 24
  • [22] Association Analysis Between Catechol-O-Methyltransferase Expression and Cognitive Function in Patients with Schizophrenia, Bipolar Disorder, or Major Depression
    Ni, Peiyan
    Liu, Manli
    Wang, Dequan
    Tian, Yang
    Zhao, Liansheng
    Wei, Jinxue
    Yu, Xueli
    Qi, Xueyu
    Li, Xiaojing
    Yu, Hua
    Ni, Rongjun
    Ma, Xiaohong
    Deng, Wei
    Guo, Wanjun
    Wang, Qiang
    Li, Tao
    NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2021, 17 : 567 - 574
  • [23] Illness history: Not associated with remission during treatment of major depression in 515 mood disorder patients
    Baldessarini, Ross J.
    Tondo, Leonardo
    Visioli, Caterina
    Vazquez, Gustavo H.
    JOURNAL OF AFFECTIVE DISORDERS, 2016, 191 : 118 - 122
  • [24] The Association of Single Nucleotide Polymorphisms in the Catechol-O-Methyltransferase Gene and Pain Scores in Female Patients With Major Depressive Disorder
    Fijal, Bonnie
    Perlis, Roy H.
    Heinloth, Alexandra N.
    Houston, John P.
    JOURNAL OF PAIN, 2010, 11 (09) : 910 - 915
  • [25] The Catechol-O-Methyltransferase and Dopamine Transporter Genes Moderated the Impact of Peer Relationships on Adolescent Depressive Symptoms: A Gene-Gene-Environment Study
    Cao, Yanmiao
    Lin, Xiaonan
    Chen, Liang
    Ji, Linqin
    Zhang, Wenxin
    JOURNAL OF YOUTH AND ADOLESCENCE, 2018, 47 (11) : 2468 - 2480
  • [26] Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene
    Mill, Jonathan
    Dempster, Emma
    Caspi, Avshalom
    Williams, Benjamin
    Moffitt, Terrie
    Craig, Ian
    AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2006, 141B (04) : 421 - 425
  • [27] Influence of catechol-O-methyltransferase enzyme gene polymorphism on alcohol and tobacco consumption in North Indian treatment seeking population
    Quraishi, Rizwana
    Sharma, Jaydeep
    Jain, Raka
    Ambekar, Atul
    INDIAN JOURNAL OF PSYCHIATRY, 2021, 63 (03) : 240 - 244
  • [28] Genotypic and Haplotypic Association of Catechol-O-Methyltransferase rs4680 and rs4818 Gene Polymorphisms with Particular Clinical Symptoms in Schizophrenia
    Sagud, Marina
    Tudor, Lucija
    Erjavec, Gordana Nedic
    Perkovic, Matea Nikolac
    Uzun, Suzana
    Mimica, Ninoslav
    Madzarac, Zoran
    Zivkovic, Maja
    Kozumplik, Oliver
    Konjevod, Marcela
    Strac, Dubravka Svob
    Pivac, Nela
    GENES, 2023, 14 (07)
  • [29] The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness
    Salo, Johanna
    Pulkki-Raback, Laura
    Hintsanen, Mirka
    Lehtimaki, Terho
    Keltikangas-Jarvinen, Liisa
    PSYCHIATRIC GENETICS, 2010, 20 (06) : 273 - 281
  • [30] Catechol-O-methyltransferase gene variants may associate with negative symptom response and plasma concentrations of prolactin in schizophrenia after amisulpride treatment
    Chen, Chun-Yen
    Yeh, Yi-Wei
    Kuo, Shin-Chang
    Ho, Pei-Shen
    Liang, Chih-Sung
    Yen, Che-Hung
    Lu, Ru-Band
    Huang, San-Yuan
    PSYCHONEUROENDOCRINOLOGY, 2016, 65 : 67 - 75
1234