Prescription of antipsychotics in people with dementiala

被引:16
作者
Ballard, Clive [1 ]
Corbett, Anne [1 ]
Howard, Robert [2 ]
机构
[1] Kings Coll London, Wolfson Ctr Age Related Dis, London SE1 1UL, England
[2] Kings Coll London, Inst Psychiat, London SE1 1UL, England
关键词
RISK; MORTALITY;
D O I
10.1192/bjp.bp.113.128710
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Gerhard et al clarify our understanding of mortality associated with antipsychotic use in people with dementia, by demonstrating a clear dose relationship and highlighting key questions regarding the relative mortality risk of different atypical antipsychotics. The study also suggests that antipsychotics may confer risks of increased mortality in older people without dementia.
引用
收藏
页码:4 / 5
页数:2
相关论文
共 10 条
  • [1] Alzheimer's Society, 2013, OPT TREATM CAR BEH P
  • [2] [Anonymous], IN PRESS
  • [3] [Anonymous], 2012, NAT DEM ANT PRESCR A
  • [4] A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (the DART-AD trial)
    Ballard, Clive
    Lana, Marisa Margallo
    Theodoulou, Megan
    Douglas, Simon
    McShane, Rupert
    Jacoby, Robin
    Kossakowski, Katja
    Yu, Ly-Mee
    Juszczak, Edmund
    [J]. PLOS MEDICINE, 2008, 5 (04) : 587 - 599
  • [5] Neuroleptic drugs in dementia: benefits and harm
    Ballard, Clive
    Howard, Robert
    [J]. NATURE REVIEWS NEUROSCIENCE, 2006, 7 (06) : 492 - 500
  • [6] Management of agitation and aggression associated with Alzheimer disease
    Ballard, Clive G.
    Gauthier, Serge
    Cummings, Jeffrey L.
    Brodaty, Henry
    Grossberg, George T.
    Robert, Philippe
    Lyketsos, Constantine G.
    [J]. NATURE REVIEWS NEUROLOGY, 2009, 5 (05) : 245 - 255
  • [7] Relapse Risk after Discontinuation of Risperidone in Alzheimer's Disease
    Devanand, D. P.
    Mintzer, Jacobo
    Schultz, Susan K.
    Andrews, Howard F.
    Sultzer, David L.
    de la Pena, Danilo
    Gupta, Sanjay
    Colon, Sylvia
    Schimming, Corbett
    Pelton, Gregory H.
    Levin, Bruce
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (16) : 1497 - 1507
  • [8] Comparative mortality risks of antipsychotic medications in community-dwelling older adults
    Gerhard, T.
    Huybrechts, K.
    Olfson, M.
    Schneeweiss, S.
    Bobo, W. V.
    Doraiswamy, P. M.
    Devanand, D. P.
    Lucas, J. A.
    Huang, C.
    Malka, E. S.
    Levin, R.
    Crystal, S.
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 2014, 205 (01) : 44 - 51
  • [9] Risk of Mortality Among Individual Antipsychotics in Patients With Dementia
    Kales, Helen C.
    Kim, Hyungjin Myra
    Zivin, Kara
    Valenstein, Marcia
    Seyfried, Lisa S.
    Chiang, Claire
    Cunningham, Francesca
    Schneider, Lon S.
    Blow, Frederic C.
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 2012, 169 (01) : 71 - 79
  • [10] Risk of death with atypical antipsychotic drug treatment for dementia - Meta-analysis of randomized placebo-controlled trials
    Schneider, LS
    Dagerman, KS
    Insel, P
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 294 (15): : 1934 - 1943