Glaucoma medications, preservatives and the ocular surface

被引：8

作者：

Aptel, F. ^{[1
]}

Labbe, A. ^{[2
,3
]}

Baudouin, C. ^{[2
,3
]}

Bron, A. ^{[4
]}

Lachkar, Y. ^{[5
]}

Sellem, E. ^{[6
]}

Renard, J. -P. ^{[7
]}

Nordmann, J. -P. ^{[2
]}

Rouland, J. -F. ^{[8
]}

Denis, P. ^{[9
]}

机构：

[1] Ctr Hosp Univ, F-38700 La Tronche, France

[2] Ctr Hosp Natl Ophtalmol Quinze Vingts, F-75012 Paris, France

[3] Hop Ambroise Pare, AP HP, F-92100 Boulogne, France

[4] Ctr Hosp Univ, F-21000 Dijon, France

[5] Grp Hosp St Joseph, F-75674 Paris, France

[6] Ctr Ophtalmol Kleber, F-69006 Lyon, France

[7] Hop Instruct Armees Val de Grace, F-75005 Paris, France

[8] Ctr Hosp Reg Univ, F-59000 Lille, France

[9] Hosp Civils Lyon, Hop Croix Rousse, F-69004 Lyon, France

来源：

JOURNAL FRANCAIS D OPHTALMOLOGIE | 2014年 / 37卷 / 09期

关键词：

Glaucoma; Medications; Eye drop; Preservative; Benzalkonium chloride; Ocular surface; Dry eye; Toxicity; Tolerability; SELECTIVE LASER TRABECULOPLASTY; TIMOLOL FIXED COMBINATIONS; INTRAOCULAR-PRESSURE; RISK-FACTORS; BENZALKONIUM CHLORIDE; PROSTAGLANDIN ANALOGS; PREVALENCE; EFFICACY; TOLERABILITY; LATANOPROST;

D O I：

10.1016/j.jfo.2014.06.005

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Several clinical and experimental studies have demonstrated that ocular surface disease is common in glaucoma patients receiving chronic glaucoma drops, and that the preservatives in these drops play a major role in the occurrence of ocular surface disease. These ocular surface changes may induce both symptoms reported by the patients and anterior segment clinical signs, and should be systematically assessed by history and exam in all glaucoma patients. In these patients with ocular surface disease, reducing the amount of preservatives administered to the eye should be strived for, rather than adding additional eye drops to alleviate or mask the side effects of the glaucoma drops. (C) 2014 Elsevier Masson SAS. All rights reserved.

引用

页码：728 / 736

页数：9

共 52 条

[1] Effects of SofZia-preserved travoprost and benzalkonium chloride-preserved latanoprost on the ocular surface - a multicentre randomized single-masked study [J].