The improvement of pumpkin(Cucurbita moschata Duch ex Poir.) for intensive cultivation necessitates genetic studies, wherein, heterosis and combing ability were studied in half di-allel fashion involving bushy plants and butternut fruits. The genotypes, P-3621 was best general combiner for short vine, internode, equatorial diameter and high fruit shape index, P-6242 for pulp thickness, P-2211 for number of primary branches, P-10224 for polar diameter as well as vegetative growth and P-1343 for petiole length. However, high specific combining ability (SCA) in P-10224 x P-6242, PS x P-6242, P-41212 x P-2211, PS x P-364, P-41212 x P-6242, P-10224 x P-2211 revealed the occurrence of both additive and non-additive gene effects with the predominance of non-additive effects (sigma 2SCA/sigma 2GCA > 1) in the inheritance of bushy and butternut traits, which can be exploited through heterosis breeding and recurrent selection in pumpkin. The hybrids, P-3621 x P-2211, P-6711 x P-2211 and P-6711 x P-6242 had high pulp thickness as well as comparable yield potential with the check hybrids and could be exploited for commercial cultivation.