Disseminated varicella-zoster virus infection with hemorrhagic gastritis during the course of chronic lymphocytic leukemia: Case report and literature review

被引：7
作者：
Serris, A. [1 ,2 ]
Michot, J. -M. [1 ,2 ]
Fourn, E. [1 ,2 ]
Le Bras, P. [1 ,2 ]
Dollat, M. [1 ,2 ]
Hirsch, G. [1 ,2 ]
Pallier, C. [2 ,3 ]
Carbonnel, F. [2 ,4 ]
Tertian, G. [2 ,5 ]
Lambotte, O. [1 ,2 ]
机构：
[1] Hop Bicetre, AP HP, Serv Med Interne, F-94275 Le Kremlin Bicetre, France
[2] Univ Paris Sud, F-94275 Le Kremlin Bicetre, France
[3] Hop Bicetre, AP HP, Serv Microbiol & Virol, F-94275 Le Kremlin Bicetre, France
[4] Hop Bicetre, AP HP, Serv Gastroenterol, F-94275 Le Kremlin Bicetre, France
[5] Hop Bicetre, AP HP, Serv Hematol Biol, F-94275 Le Kremlin Bicetre, France
来源：
REVUE DE MEDECINE INTERNE | 2014年 / 35卷 / 05期
关键词：
Varicella-zoster virus; Gastrointestinal hemorrhage; Chronic lymphocytic leukemia; Immunocompromised patient; BONE-MARROW-TRANSPLANTATION; STEM-CELL TRANSPLANTATION; ACUTE ABDOMEN; ABDOMINAL-PAIN; HERPES-ZOSTER; PATIENT;
D O I：
10.1016/j.revmed.2013.05.004
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. - The reactivation of varicella-zoster virus occurs in immunocompromised patients, especially in cases of hematological malignancy. Disseminated reactivation could involve digestive tract with life-threatening condition. Case report. - A 76-year-old woman, with a history of chronic lymphocytic leukemia, presented with left hypochondrium pain, and a vesicular rash with hemorrhagic shock that revealed an hemorrhagic gastritis due to varicella-zoster virus. The literature review identified 28 additional cases of gastrointestinal mucosal damage during reactivation of varicella-zoster virus. Mortality is 40%. We report here the first case in the course of low-grade lymphoid malignancy. Conclusion. - Acute gastrointestinal symptoms in immunocompromised patients should evoke a varicella-zoster virus reactivation with gastrointestinal involvement. This clinical manifestation, although rare, should not be ignored because of its severity. (C) 2013 Societe nationale francaise de medecine interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：337 / 340
页数：4
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