Olfactory receptor-encoding genes and pseudogenes are expressed in humans

被引：28

作者：

Crowe, ML ^{[1
]}

Perry, BN ^{[1
]}

Connerton, IF ^{[1
]}

机构：

[1] INST FOOD RES,DEPT PROT ENGN,READING RG6 6BZ,BERKS,ENGLAND

来源：

GENE | 1996年 / 169卷 / 02期

关键词：

olfaction; odorant receptor; neuron; gene regulation; gene cloning; cDNA; G-protein-coupled receptor;

D O I：

10.1016/0378-1119(95)00849-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A putative olfactory receptor-encoding gene was cloned from human genomic DNA and shown to be expressed by isolation of a full-length cDNA from olfactory tissue. A second cDNA clone was found to encode an olfactory receptor pseudogene. The expression of a pseudogene from the olfactory gene repertoire, in neurons which express only a single receptor type, implies that many neurons will be non-functional.

引用

页码：247 / 249

页数：3

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