Green synthesis of 5-arylidene-2,4-thiazolidinedione, 5-benzylidene rhodanine and dihydrothiophene derivatives catalyzed by hydrated ionic liquid tetrabutylammonium hydroxide in aqueous medium

被引：21

作者：

Khazaei, Ardeshir ^{[1
]}

Veisi, Hojat ^{[2
]}

Safaei, Maryam ^{[2
]}

Ahmadian, Hossein ^{[2
]}

机构：

[1] Bu Ali Sina Univ, Fac Chem, Hamadan, Iran

[2] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran

来源：

JOURNAL OF SULFUR CHEMISTRY | 2014年 / 35卷 / 03期

关键词：

dihydrothiophenes; rhodanines; ionic liquid; 2,4-thiazolidinediones; ONE-POT SYNTHESIS; INHIBITORS;

D O I：

10.1080/17415993.2013.860142

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient synthesis of 5-arylidene-2,4-thiazolidinediones and 5-benzylidene rhodanines by the Knoevenagel condensation of 2,4-thiazolidinedione or rhodanine with aromatic aldehydes was studied. It proceeded smoothly in the presence of tetrabutylammonium hydroxide/H O-2-EtOH to afford the corresponding products in high yields at 50 degrees C. Also, a series of dihydrothiophene derivatives were synthesized via the four-component reaction of aldehyde, malonitrile, 2,4-thiazolidinedione, and piperidine in the presence of Bu4NOH as a basic ionic liquid in aqueous medium. This new method offers several advantages, such as excellent yields, short reaction times, and simple procedure.

引用

页码：270 / 278

页数：9

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