Environmental Epigenetics and Effects on Male Fertility

被引：24

作者：

Guerrero-Bosagna, Carlos ^{[1
]}

Skinner, Michael K. ^{[1
]}

机构：

[1] Washington State Univ, Sch Biol Sci, Ctr Reprod Biol, Pullman, WA 99164 USA

来源：

GENETIC DAMAGE IN HUMAN SPERMATOZOA | 2014年 / 791卷

关键词：

Testis; Spermatogenesis; Sperm; Epigenetics; Transgenerational; DNA Methylation; Epimutations; SERTOLI-CELL DIFFERENTIATION; MALE SEX DETERMINATION; DNA METHYLATION; TRANSGENERATIONAL INHERITANCE; POLYCHLORINATED-BIPHENYLS; TESTIS DIFFERENTIATION; GONADAL DEVELOPMENT; PRENATAL EXPOSURE; SOX9; EXPRESSION; IMPRINTED LOCI;

D O I：

10.1007/978-1-4614-7783-9_5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Environmental exposures to factors such as toxicants or nutrition can have impacts on testis biology and male fertility. The ability of these factors to influence epigenetic mechanisms in early life exposures or from ancestral exposures will be reviewed. A growing number of examples suggest environmental epigenetics will be a critical factor to consider in male reproduction.

引用

页码：67 / 81

页数：15

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