Comparison of liver SUV using unenhanced CT versus contrast- enhanced CT for attenuation correction in 18 F-FDGPET/CT

被引：7
作者：
ter Voert, Edwin E. G. W. [1 ]
van Laarhoven, Hanneke W. M. [2 ,4 ]
Kok, Peter J. M. [3 ]
Oyen, Wim J. G. [3 ]
Visser, Eric P. [3 ]
de Geus-Oei, Lioe-Fee [3 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Radiol, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Med Oncol, NL-6500 HB Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Med Ctr, Dept Nucl Med, NL-6500 HB Nijmegen, Netherlands
[4] Univ Amsterdam, Acad Med Ctr, Dept Med Oncol, NL-1105 AZ Amsterdam, Netherlands
来源：
NUCLEAR MEDICINE COMMUNICATIONS | 2014年 / 35卷 / 05期
关键词：
attenuation correction; contrast-enhanced CT; F-18-FDG; liver; PET; PET/CT;
D O I：
10.1097/MNM.0000000000000086
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
AimThe aim of the study was to compare standardized uptake values (SUVs) in liver tissue obtained using whole-body unenhanced low-dose computed tomography (CT) with those obtained using contrast-enhanced high-dose CT for PET attenuation correction in PET/CT scanning.Materials and methodsTen patients scheduled for F-18-FDG PET and contrast-enhanced CT of the abdomen were included in this study. PET data were corrected for attenuation using both unenhanced low-dose CT images and contrast-enhanced high-dose CT images. Differences in SUVmean and SUVmax were compared in three liver regions.ResultsThe average SUVmean and SUVmax of all regions were 2.43 and 2.91 g/cm(3) in the unenhanced data set and 2.53 and 3.17 g/cm(3) in the enhanced data set, respectively.ConclusionSUV(mean) and SUVmax were significantly elevated in liver tissue when using PET images corrected for attenuation with contrast-enhanced high-dose CT compared with PET images corrected with unenhanced low-dose CT. Although the differences may not be relevant in daily clinical practice, unenhanced and contrast-enhanced CT should not be selected randomly for attenuation correction if exact quantitative results are required.
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收藏
页码：472 / 477
页数：6
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