Asymmetric rhodium carbenoid insertion into the Si-H bond

被引：68

作者：

Buck, RT

Doyle, MP

Drysdale, MJ

Ferris, L

Forbes, DC

Haigh, D

Moody, CJ

Pearson, ND

Zhou, QL

机构：

[1] TRINITY UNIV,DEPT CHEM,SAN ANTONIO,TX 78212

[2] UNIV LOUGHBOROUGH,DEPT CHEM,LOUGHBOROUGH LE11 3TU,LEICS,ENGLAND

[3] GLAXO WELLCOME RES & DEV LTD,MED RES CTR,STEVENAGE SG1 2NY,HERTS,ENGLAND

[4] SMITHKLINE BEECHAM PHARMACEUT,EPSOM KT18 5XQ,SURREY,ENGLAND

[5] SMITHKLINE BEECHAM PHARMACEUT,BETCHWORTH RH3 7AL,SURREY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 42期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0040-4039(96)01679-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Decomposition of methyl 2-diazophenylacetate in the presence of dimethylphenylsilane and a chiral dirhodium(II) catalyst results in SI-H insertion of the intermediate carbenoid with varying degrees of enantioselectivity (up to 47% ee). Copyright (C) 1996 Elsevier Science Ltd

引用

收藏

页码：7631 / 7634

页数：4

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