Prostate-specific Membrane Antigen-targeted Ligand Positron Emission Tomography/Computed Tomography and Immunohistochemical Findings in a Patient With Synchronous Metastatic Penile and Prostate Cancer

被引：9

作者：

Froehner, Michael ^{[1
]}

Kuithan, Friederike

Zoephel, Klaus

Heberling, Ulrike

Laniado, Michael

Wirth, Manfred P.

机构：

[1] Tech Univ Dresden, Dept Urol, Univ Hosp Carl Gustav Carus, Fetscherstr 74, D-01307 Dresden, Germany

来源：

UROLOGY | 2017年 / 101卷

关键词：

EXPRESSION; CARCINOMA;

D O I：

10.1016/j.urology.2016.11.040

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 68-year-old man presented with synchronous metastatic penile and prostate cancer. 68Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) revealed tracer uptake in inguinal, pelvic, and retroperitoneal metastases. Lymph node biopsies and immunohistochemical staining revealed that both cancers involved the lymph nodes and expressed PSMA. In the deposits of penile squamous cell carcinoma, PSMA expression was seen in tumor vessels and may explain the PSMA-PET/CT positivity of inguinal nodes involved in squamous cell carcinoma. The interpretation of imaging in synchronous tumors should take this fact into consideration. (C) 2016 Elsevier Inc.

引用

页码：E5 / E6

页数：2

共 50 条

[41] Metastatic Thyroid Cartilage Lesion from Prostatic Adenocarcinoma on 68Ga-Prostate-Specific Membrane Antigen Positron Emission Tomography-Computed Tomography Scan: Case Series [J].

Gupta, Nitin ;

Verma, Ritu ;

Belho, Ethel Shangne .

INDIAN JOURNAL OF NUCLEAR MEDICINE, 2021, 36 (02) :183-188

[42] Diagnostic Performance of Radiolabeled Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Primary Lymph Node Staging in Newly Diagnosed Intermediate to High-Risk Prostate Cancer Patients: A Systematic Review and Meta-Analysis [J].

Kim, Seong-Jang ;

Lee, Sang-Woo ;

Ha, Hong Koo .

UROLOGIA INTERNATIONALIS, 2019, 102 (01) :27-36

[43] Optimal Timing of Prostate Specific Membrane Antigen Positron Emission Tomography/Computerized Tomography for Biochemical Recurrence after Radical Prostatectomy [J].

Luiting, Henk B. ;

van Leeuwen, Pim J. ;

Remmers, Sebastiaan ;

Donswijk, Maarten ;

Busstra, Martijn B. ;

Bakker, Ingrid L. ;

Brabander, T. ;

Stokkel, Marcel ;

van der Poel, Henk G. ;

Roobol, Monique J. .

JOURNAL OF UROLOGY, 2020, 204 (03) :503-509

[44] Comparative study between 68Ga-prostate-specific membrane antigen positron emission tomography and conventional imaging in the initial staging of prostate cancer [J].

Wong, Hui Sze ;

Leung, John ;

Bartholomeusz, Dylan ;

Sutherland, Peter ;

Le, Hien ;

Nottage, Michelle ;

Iankov, Ivan ;

Chang, Joe H. .

JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 2018, 62 (06) :816-822

[45] Prostate Specific Membrane Antigen Positron Emission Tomography/Computerized Tomography in the Evaluation of Initial Response in Candidates Who Underwent Salvage Radiation Therapy after Radical Prostatectomy for Prostate Cancer [J].

Meijer, Dennie ;

Luiting, Henk B. ;

van Leeuwen, Pim J. ;

Remmers, Sebastiaan ;

Jansen, Bernard H. E. ;

Bodar, Yves J. L. ;

Witteveen, Thelma ;

Schaake, Eva E. ;

van der Poel, Henk G. ;

Wondergem, Maurits ;

Busstra, Martijn B. ;

Nieuwenhuijzen, Jakko A. ;

Meijnen, Philip ;

Brabander, Tessa ;

van Moorselaar, R. Jeroen A. ;

Hendrikse, N. Harry ;

Oprea-Lager, Daniela E. ;

Roobol, Monique J. ;

Vis, Andre N. .

JOURNAL OF UROLOGY, 2021, 205 (04) :1100-1108

[46] Prostate-specific membrane antigen-targeted liposomes specifically deliver the Zn2+ chelator TPEN inducing oxidative stress in prostate cancer cells [J].

Stuart, Christopher H. ;

Singh, Ravi ;

Smith, Thomas L. ;

D'Agostino, Ralph, Jr. ;

Caudell, David ;

Balaji, K. C. ;

Gmeiner, William H. .

NANOMEDICINE, 2016, 11 (10) :1207-1222

[47] Diagnostic Performance of 68Gallium Labelled Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography and Magnetic Resonance Imaging for Staging the Prostate Cancer with Intermediate or High Risk Prior to Radical Prostatectomy: A Systematic Review and Meta-Analysis [J].

Wu, Hui ;

Xu, Ting ;

Wang, Xiao ;

Yu, Yong-Bo ;

Fan, Zhong-Yuan ;

Li, Dan-Xia ;

Luo, Lei ;

Yang, Xue-Cheng ;

Jiao, Wei ;

Niu, Hai-Tao .

WORLD JOURNAL OF MENS HEALTH, 2020, 38 (02) :208-219

[48] A Prospective Pilot Study of 89Zr-J591/Prostate Specific Membrane Antigen Positron Emission Tomography in Men with Localized Prostate Cancer Undergoing Radical Prostatectomy [J].

Osborne, Joseph R. ;

Green, David A. ;

Spratt, Daniel E. ;

Lyashchenko, Serge ;

Fareedy, Shoaib B. ;

Robinson, Brian D. ;

Beattie, Bradley J. ;

Jain, Manu ;

Lewis, Jason S. ;

Christos, Paul ;

Larson, Steven M. ;

Bander, Neil H. ;

Scherr, Douglas S. .

JOURNAL OF UROLOGY, 2014, 191 (05) :1439-1445

[49] Prostate-specific membrane antigen (PSMA)-expressing melanoma metastases in a patient with prostate cancer and melanoma [J].

Hirsch, Johanna ;

Voltin, Conrad-Amadeus ;

Schmiel, Marcel ;

Kreuzberg, Nicole ;

Mauch, Cornelia ;

Franklin, Cindy .

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2024, 22 (03) :446-449

[50] Uptake of the prostate-specific membrane antigen-targeted PET radiotracer 18F-DCFPyL in elastofibroma dorsi [J].

Gorin, Michael A. ;

Marashdeh, Wael ;

Ross, Ashley E. ;

Allaf, Mohammad E. ;

Pienta, Kenneth J. ;

Pomper, Martin G. ;

Rowe, Steven P. .

NUCLEAR MEDICINE COMMUNICATIONS, 2017, 38 (09) :795-798

← 1 2 3 4 5 →