An ace model for SARS-CoV-2 infection

被引：4
作者：
Major, Jack [1 ]
Wack, Andreas [1 ]
机构：
[1] Francis Crick Inst, Immunoregulat Lab, London, England
来源：
JOURNAL OF EXPERIMENTAL MEDICINE | 2020年 / 217卷 / 12期
关键词：
INTERFERON;
D O I：
10.1084/jem.20201748
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Developing effective in vivo models for SARS-CoV-2 infection is crucial for mechanistic studies of COVID-19 disease progression. In this issue of JEM, Israelow et al. (https://doi.org/10.1084/jem.20201241) generate a model that supports SARS-CoV-2 infection in mice, which they use to characterize type I IFN-driven pulmonary inflammation.
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页数：3
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