An ace model for SARS-CoV-2 infection

被引：3

作者：

Major, Jack ^{[1
]}

Wack, Andreas ^{[1
]}

机构：

[1] Francis Crick Inst, Immunoregulat Lab, London, England

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 2020年 / 217卷 / 12期

基金：

英国医学研究理事会;

关键词：

INTERFERON;

D O I：

10.1084/jem.20201748

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Developing effective in vivo models for SARS-CoV-2 infection is crucial for mechanistic studies of COVID-19 disease progression. In this issue of JEM, Israelow et al. (https://doi.org/10.1084/jem.20201241) generate a model that supports SARS-CoV-2 infection in mice, which they use to characterize type I IFN-driven pulmonary inflammation.

引用

页数：3

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