Synthesis of some new 5-(1-phenyl-1H-1,2,3-triazol-4-yl)-1H-tetrazoles and evaluation of their antimicrobial activity

被引：3

作者：

Naresh, E. ^{[1
]}

Bhaskar, K. ^{[1
]}

Linga goud, G. ^{[1
]}

机构：

[1] Osmania Univ, Dept Chem, Green & Med Chem Lab, Hyderabad 500007, Andhra Pradesh, India

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2016年 / 86卷 / 12期

关键词：

triazole aldehyde; triazlyl tetrazole; cupper acetate; and antibacterial activity;

D O I：

10.1134/S1070363216120513

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

a series of new tetrazole derivatives were synthesized by a reaction of triazole oxime with sodium azide catalyzed by copper acetate and isolated with high yield under mild conditions. All synthesized compounds were characterized by IR, NMR, and MS data. Evaluation of antimicrobial activity of the products against Gram-positive and Gram-negative bacterial and antifungal strains has been carried out. Among the compounds 3a, 3c, 3e, and 3f exhibited high antibacterial activity and compounds 3a, 3c, 3e demonstrated high antifungal activity.

引用

页码：2862 / 2864

页数：3

共 10 条

[1]

Butler R N., 1996, Comprehensive Heterocyclic Chemistry II, V4, P621, DOI DOI 10.1016/B978-008096518-5.00095-2

[2]

Butler R.N., 1984, COMPREHENSIVE HETERO, V5, P791, DOI [10.1016/B978-008096519-2.00081-3, DOI 10.1016/B978-008096519-2.00081-3]

[3]

Carlucci L, 1999, ANGEW CHEM INT EDIT, V38, P3488

[4]

Gaponik P.N., 2006, RUSS CHEM REV+, V75, P507, DOI [10.1070/RC2006v075n06ABEH003601, DOI 10.1070/RC2006V075N06ABEH003601]

[5]

HABU T, 1991, J IMAGING SCI, V35, P202

[6]

Hiskey M., 2000, PROC INT PYROTECH SE, V27, P3

[7]

ITOH F, 1995, CHEM PHARM BULL, V43, P230

[8]

Ortstein P. L., 1993, BIOORG MED CHEM LETT, V3, P43

[9]

Singh H, 1980, Prog Med Chem, V17, P151, DOI 10.1016/S0079-6468(08)70159-0

[10] POTENT INHIBITORS OF PLATELET-AGGREGATION BASED UPON THE ARG-GLY-ASP-PHE SEQUENCE OF FIBRINOGEN - A PROPOSAL ON THE NATURE OF THE BINDING INTERACTION BETWEEN THE ASP-CARBOXYLATE OF RGDX MIMETICS AND THE PLATELET GP IIB-IIIA RECEPTOR [J].

ZABLOCKI, JA ;

MIYANO, M ;

RAO, SN ;

PANZERKNODLE, S ;

NICHOLSON, N ;

FEIGEN, L .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (26) :4914-4917

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