Restrictions in quality of life in colorectal cancer patients over three years after diagnosis: A population based study

被引:106
作者
Arndt, Volker
Merx, Henrike
Stegmaier, Christa
Ziegler, Hartwig
Brenner, Hermann
机构
[1] German Ctr Res Ageing, Dept Epidemiol, D-69115 Heidelberg, Germany
[2] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, D-69115 Heidelberg, Germany
[3] Univ Ulm, Dept Epidemiol, D-89081 Ulm, Germany
[4] Saarland Canc Registry, D-66119 Saarbrucken, Germany
关键词
adaptation; psychological; age factors; cohort studies; chemotherapy; colostomy; colorectal neoplasms; comparative study; cross-sectional studies; follow-up studies;
D O I
10.1016/j.ejca.2006.01.059
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Despite the burden and prevalence of colorectal cancer (CRC), there is only limited information regarding quality of life of patients who have survived beyond the first year post treatment. We assessed quality of life in a population-based cohort of 309 patients with CRC from Saarland (Germany) one and three years after diagnosis using the QLQ-C30 questionnaire and the tumour specific module QLQ-CR38. When compared with reference data from the general population, most patients with CRC reported high overall quality of life and only small deficits in physical functioning but deficits in emotional and social functioning persist over years in patients with colorectal cancer. Improvements in quality of life from the first to the third year after diagnosis in patients who remained free of disease were very modest and limited to less financial difficulties, a better future perspective and fewer stoma-related problems.
引用
收藏
页码:1848 / 1857
页数:10
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