Non-enzymatic amperometric sensing of hydrogen peroxide at a CuS modified electrode for the determination of urine H2O2

被引：46
作者：
Dutta, Amit Kumar [1 ]
Das, Sudipto [1 ]
Samanta, Partha Kumar [1 ]
Roy, Shounak [1 ]
Adhikary, Bibhutosh [1 ]
Biswas, Papu [1 ]
机构：
[1] Indian Inst Engn Sci & Technol, Dept Chem, Howrah 711103, W Bengal, India
来源：
ELECTROCHIMICA ACTA | 2014年 / 144卷
关键词：
CuS nanoparticles; Electrochemical behavior; Non-enzymatic amperomatric sensor; Hydrogen peroxide; Human urine; HORSERADISH-PEROXIDASE; SPECTROPHOTOMETRIC DETERMINATION; ELECTROCHEMICAL SENSORS; MIMIC PEROXIDASE; BIOSENSOR; NANOPARTICLES; GLUCOSE; FILM; HEMOGLOBIN; REDUCTION;
D O I：
10.1016/j.electacta.2014.08.051
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
A new electrochemical sensor based on CuS nanoparticles for detection and estimation of hydrogen peroxide in human urine has been developed. The non-enzymatic amperometric sensor was fabricated by immobilizing the synthesized CuS nanoparticles on surface of a glassy carbon electrode (GCE) using direct drop coating techniques. The proposed sensor shows high electron transfer ability, good electrochemical behavior and exhibits electrocatalytic activity towards reduction of hydrogen peroxide (H2O2) in aqueous medium. Under optimal conditions, the electrocatalytic response of the sensor was proportional to the H2O2 concentration in the range from 10 to 1900 mu M with a detection limit of 1.1 mu M (S/N = 3). In addition, the CuS/GCE based sensor displayed faster response, high sensitivity and good anti interference ability. Based on this electrochemical process, the concentration of H2O2 in human urine can be monitored conveniently. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：282 / 287
页数：6
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