68Ga-Prostate-Specific Membrane Antigen PET/CT in Triple-Negative Breast Cancer

被引：26

作者：

Passah, Averilicia ^{[1
]}

Arora, Saurabh ^{[1
]}

Damle, Nishikant Avinash ^{[1
]}

Tripathi, Madhavi ^{[1
]}

Bal, Chandrasekhar ^{[1
]}

Subudhi, T. Kishan ^{[1
]}

Arora, Geetanjali ^{[1
]}

机构：

[1] All India Inst Med Sci, Dept Nucl Med, New Delhi 110029, India

来源：

CLINICAL NUCLEAR MEDICINE | 2018年 / 43卷 / 06期

关键词：

PSMA PET; CT; theranostics; triple-negative breast cancer; PSMA EXPRESSION; GA-68-PSMA; CARCINOMA;

D O I：

10.1097/RLU.0000000000002071

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The prostate-specific membrane antigen (PSMA) is a transmembrane protein with elevated expression in prostate cancer cells. Breast cancer also shows PSMA expression. We present the case of a 30-year-old woman with triple-negative bilateral breast carcinoma who underwent bilateral mastectomy, chemotherapy, and radiotherapy. She developed a left chest wall and liver recurrence after primary therapy. Her recurrent disease was also triple-negative. In view of the known poor prognosis and very limited therapeutic options, we performed 68Ga-PSMA PET/CT scan to explore the possibility of PSMA-based therapy as a future option after exhausting standard-of-care treatments. © 2018 Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：460 / 461

页数：2

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