Surface micropatterning to regulate cell functions

被引：436
作者：
Ito, Y [1 ]
机构：
[1] Univ Tokushima, Fac Engn, Dept Biol Sci & Technol, Tokushima 7708506, Japan
[2] JST, PRESTO, Kyoto 6190237, Japan
来源：
BIOMATERIALS | 1999年 / 20卷 / 23-24期
关键词：
micropatterning; tissue engineering; surface modification; immobilization; cell growth factor; cell adhesion factor;
D O I：
10.1016/S0142-9612(99)00162-3
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The current technology available for surface microfabrication with macromolecules to regulate cell functions is reviewed. Surface topology, and surface modification with hydrophilic or hydrophobic polymers, electrically charged polymers, stimuli-responsive macromolecules, polysaccharide, and proteins involving adhesion or growth factors are discussed. These surface-microfabricated biomaterials had the ability to regulate cell functions such as proliferation, differentiation, and apoptosis. (C) 1999 Elsevier Science Ltd. All rights reserved.
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收藏
页码：2333 / 2342
页数：10
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