Conversion of diploidy to haploidy - Individuals susceptible to multigene disorders may now be spotted more easily.

被引：209

作者：

Yan, H ^{[1
]}

Papadopoulos, N

Marra, G

Perrera, C

Jiricny, J

Boland, CR

Lynch, HT

Chadwick, RB

de la Chapelle, A

Berg, K

Eshleman, JR

Yuan, WS

Markowitz, S

Laken, SJ

Lengauer, C

Kinzler, KW

Vogelstein, B

机构：

[1] Johns Hopkins Univ, Howard Hughes Med Inst, Ctr Oncol, Dept Math Sci, Baltimore, MD 21231 USA

[2] Johns Hopkins Univ, Dept Pathol, Baltimore, MD 21231 USA

[3] Columbia Univ, Inst Canc Genet, New York, NY 10032 USA

[4] Inst Med Radiobiol, CH-8008 Zurich, Switzerland

[5] Univ Calif San Diego, La Jolla, CA 92093 USA

[6] Creighton Univ, Sch Med, Dept Prevent Med & Publ Hlth, Omaha, NE 68178 USA

[7] Ohio State Univ, Ctr Comprehens Canc, Human Canc Genet Program, Columbus, OH 43210 USA

[8] Case Western Reserve Univ, Howard Hughes Med Inst, Cleveland, OH 44106 USA

[9] Case Western Reserve Univ, Dept Med, Cleveland, OH 44106 USA

[10] Case Western Reserve Univ, Ireland Canc Ctr, Cleveland, OH 44106 USA

[11] Univ Hosp Cleveland, Cleveland, OH 44106 USA

来源：

NATURE | 2000年 / 403卷 / 6771期

关键词：

D O I：

10.1038/35001659

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Individuals susceptible to multigene disorders may now be spotted more easily.

引用

页码：723 / 724

页数：2

共 16 条

[1] TUMOR-SUPPRESSOR GENES STUDIED BY CELL HYBRIDIZATION AND CHROMOSOME TRANSFER [J].

ANDERSON, MJ ;

STANBRIDGE, EJ .

FASEB JOURNAL, 1993, 7 (10) :826-833

[2] IDENTIFICATION AND CHARACTERIZATION OF THE FAMILIAL ADENOMATOUS POLYPOSIS-COLI GENE [J].

GRODEN, J ;

THLIVERIS, A ;

SAMOWITZ, W ;

CARLSON, M ;

GELBERT, L ;

ALBERTSEN, H ;

JOSLYN, G ;

STEVENS, J ;

SPIRIO, L ;

ROBERTSON, M ;

SARGEANT, L ;

KRAPCHO, K ;

WOLFF, E ;

BURT, R ;

HUGHES, JP ;

WARRINGTON, J ;

MCPHERSON, J ;

WASMUTH, J ;

LEPASLIER, D ;

ABDERRAHIM, H ;

COHEN, D ;

LEPPERT, M ;

WHITE, R .

CELL, 1991, 66 (03) :589-600

[3]

HARRIS H, 1985, J CELL SCI, V79, P83

[4] NONRANDOM LOSS OF HUMAN-CHROMOSOME-3 FRAGMENTS FROM MOUSE-HUMAN MICROCELL HYBRIDS FOLLOWING PROGRESSIVE GROWTH IN SCID MICE [J].

IMREH, S ;

KHOLODNYUK, I ;

ALLIKMETTS, R ;

STANBRIDGE, EJ ;

ZABAROVSKY, ER ;

KLEIN, G .

GENES CHROMOSOMES & CANCER, 1994, 11 (04) :237-245

[5] Genetic instability in colorectal cancers [J].

Lengauer, C ;

Kinzler, KW ;

Vogelstein, B .

NATURE, 1997, 386 (6625) :623-627

[6] Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients [J].

Liu, B ;

Parsons, R ;

Papadopoulos, N ;

Nicolaides, NC ;

Lynch, HT ;

Watson, P ;

Jass, JR ;

Dunlop, M ;

Wyllie, A ;

Peltomaki, P ;

delaChapelle, A ;

Hamilton, SR ;

Vogelstein, B ;

Kinzler, KW .

NATURE MEDICINE, 1996, 2 (02) :169-174

[7]

Lynch HT, 1999, J MED GENET, V36, P801

[8]

McDaniel LD, 1997, HUM MUTAT, V10, P317, DOI 10.1002/(SICI)1098-1004(1997)10:4<317::AID-HUMU8>3.3.CO

[9]

2-J

[10] MONOALLELIC MUTATION ANALYSIS (MAMA) FOR IDENTIFYING GERMLINE MUTATIONS [J].

PAPADOPOULOS, N ;

LEACH, FS ;

KINZLER, KW ;

VOGELSTEIN, B .

NATURE GENETICS, 1995, 11 (01) :99-102

← 1 2 →