DNA hybridization arrays for gene expression analysis of human oral cancer

被引：14
作者：
Todd, R
Wong, DTW
机构：
[1] Harvard Sch Dent Med, Lab Oral & Maxillofacial Surg, Boston, MA 02115 USA
[2] Harvard Sch Dent Med, Dept Oral Med & Diagnost Sci, Div Oral Pathol, Lab Mol Pathol, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Boston, MA 02114 USA
来源：
JOURNAL OF DENTAL RESEARCH | 2002年 / 81卷 / 02期
关键词：
microarray; gene expression; oral cancer;
D O I：
10.1177/154405910208100202
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
DNA hybridization arrays permit global gene expression profiling to be done in a single experiment. The evolution and challenges of DNA hybridization arrays are reflected in the variety of experimental platforms, probe composition, hybridization/signal detection methods, and bioinformatic interpretation. In tumor biology, DNA hybridization arrays are being used for gene/gene pathway discovery, diagnosis, and therapeutic design. Similar applications are advancing our understanding of oral cancer cell biology.
引用
收藏
页码：89 / 97
页数：9
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