Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas

被引:9
作者
Fukuoka, SI [1 ]
Kern, H
Kazuki-Sugino, R
Ikeda, Y
机构
[1] Kyoto Univ, Grad Sch Agr, Uji, Kyoto 6110011, Japan
[2] Univ Marburg, Dept Cell Biol & Cell Pathol, Marburg, Germany
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2002年 / 1575卷 / 1-3期
关键词
annexing; apical localization; molecular cloning; northern blot; pancreas; zymogen granule;
D O I
10.1016/S0167-4781(02)00299-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ZAP36, a zymogen granule membrane associated protein with 36 kDa, was cloned from both canine and rat pancreas. ZAP36 is found to be a novel member of annexin IV, and showed an apical localization in exocrine pancreas and an ubiquitous expression in epithelial tissues. ZAP36 may be involved in exocytosis in apical regions of polarized cells. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:148 / 152
页数:5
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