Blueberry and Mulberry Juice Prevent Obesity Development in C57BL/6 Mice

被引：99

作者：

Wu, Tao ^{[1
,2
]}

Tang, Qiong ^{[1
]}

Gao, Zichun ^{[1
]}

Yu, Zhuoping ^{[1
]}

Song, Haizhao ^{[1
]}

Zheng, Xiaodong ^{[1
,2
]}

Chen, Wei ^{[1
,2
]}

机构：

[1] Zhejiang Univ, Coll Biosyst Engn & Food Sci, Hangzhou 310003, Zhejiang, Peoples R China

[2] Zhejiang Univ, Fuli Inst Food Sci, Hangzhou 310003, Zhejiang, Peoples R China

来源：

PLOS ONE | 2013年 / 8卷 / 10期

基金：

中国国家自然科学基金;

关键词：

BERRY ANTHOCYANINS; INSULIN-RESISTANCE; WHOLE BERRIES; WEIGHT; ANTIOXIDANT; PARAMETERS; LEPTIN; MODEL;

D O I：

10.1371/journal.pone.0077585

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Objectives: To establish whether blueberry (Vaccinium ashei) and mulberry (Morus australis Poir) juice, anthocyanin rich fruit juice, may help counteract obesity. Design: And Methods: Four-week-old C57BL/6 mice were fed a high-fat diet (HFD) with or without blueberry and mulberry juice for 12 weeks. Body weight, serum and hepatic lipids, liver and adipose tissues morphology, insulin and leptin were assessed. Results: Mice fed HFD exhibited increased body weight, insulin resistance, serum and hepatic lipids. In comparison, blueberry and mulberry juice inhibited body weight gain, decreased the serum cholesterol, reduced the resistance to insulin, attenuated lipid accumulation and decreased the leptin secretin. Conclusion: These results indicate that blueberry and mulberry juice may help counteract obesity.

引用

页数：7

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