Infectious Complications in Atopic Dermatitis

被引：42
|
作者：
Sun, Di [1 ]
Ong, Peck Y. [1 ,2 ]
机构：
[1] Univ Southern Calif, Dept Pediat, Keck Sch Med, 1975 Zonal Ave, Los Angeles, CA 90033 USA
[2] Childrens Hosp Los Angeles, Div Clin Immunol & Allergy, 4650 Sunset Blvd,MS 75, Los Angeles, CA 90027 USA
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2017年 / 37卷 / 01期
关键词：
Atopic dermatitis; Staphylococcal aureus; Eczema herpeticum; Keratinocytes; Innate; RESISTANT STAPHYLOCOCCUS-AUREUS; METHICILLIN-RESISTANT; SKIN MICROBIOME; LANGERHANS CELLS; ALPHA-TOXIN; MOLLUSCUM CONTAGIOSUM; FILAGGRIN MUTATIONS; ECZEMA HERPETICUM; SIGNAL TRANSDUCER; BARRIER FUNCTION;
D O I：
10.1016/j.iac.2016.08.015
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Atopic dermatitis is characterized by the interplay of skin barrier defects with the immune system and skin microbiome that causes patients to be at risk for infectious complications. This article reviews the pathogenesis of atopic dermatitis and the mechanisms through which patients are at risk for infection from bacterial, viral, and fungal pathogens. Although these complications may be managed acutely, prevention of secondary infections depends on a multipronged approach in the maintenance of skin integrity, control of flares, and microbial pathogens.
引用
收藏
页码：75 / +
页数：20
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