Indirect comparisons of treatment effects: Network meta-analyses

被引:2
作者
Sormani, Maria Pia [1 ]
机构
[1] Univ Genoa, Biostat Unit, Dept Hlth Sci DISSAL, Via Pastore 1, I-16132 Genoa, Italy
关键词
Indirect treatment comparisons; network meta-analysis; MULTIPLE-SCLEROSIS;
D O I
10.1177/1352458517690272
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Many therapeutic options are now available for patients with multiple sclerosis. While the efficacy of each drug has been assessed against placebo or, more recently, against interferon, no direct comparisons of these new therapies have been conducted in randomized clinical trials. Therefore, indirect treatment comparisons are needed to inform clinical decisions. In this brief report, some basic concepts about network meta-analyses that are the formal methods used to run multiple indirect treatment comparisons are reviewed when applied in the context of multiple sclerosis studies.
引用
收藏
页码:510 / 512
页数:3
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