Drugs for Acute Attack of Pediatric Migraine: A Network Meta-analysis of Randomized Controlled Trials
被引:5
作者:
Wang, Guihua
论文数: 0引用数: 0
h-index: 0
机构:
Sichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Sichuan Univ, West China Hosp 4, Chengdu, Sichuan, Peoples R ChinaSichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Wang, Guihua
[1
,2
]
Tan, Tianlin
论文数: 0引用数: 0
h-index: 0
机构:
Xindu Hosp Tradit Chinese Med, Chengdu, Sichuan, Peoples R ChinaSichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Tan, Tianlin
[3
]
Liu, Yao
论文数: 0引用数: 0
h-index: 0
机构:
Xindu Hosp Tradit Chinese Med, Chengdu, Sichuan, Peoples R ChinaSichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Liu, Yao
[3
]
Hong, Peiwei
论文数: 0引用数: 0
h-index: 0
机构:
Sichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Sichuan Univ, West China Hosp 4, Chengdu, Sichuan, Peoples R ChinaSichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
Hong, Peiwei
[1
,2
]
机构:
[1] Sichuan Univ, Dept Geriatr Med & Neurol, West China Sch Publ Hlth, Chengdu, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp 4, Chengdu, Sichuan, Peoples R China
[3] Xindu Hosp Tradit Chinese Med, Chengdu, Sichuan, Peoples R China
Migraine in pediatric is a common neurological disease, and its prevalence is varying widely. The medication for the acute attack of pediatric migraine is various. we take advantage of network meta-analysis to address the efficacy and rank of these medications. Database including Pubmed and Cochrane Library were queried using a specific searching strategy. The quality of trials enrolled was assessed according to the Cochrane collaboration'tool for assessing risk of bias. The data analysis was conducted by using the core software for Cochrane reviews (Rev Man 5.3) and the Aggregate Data Drug Information System (Addis v1.16.8). The outcomes were pain-free and pain relief at 2 hours post-dose. Totally, twenty trials with high quality including 6029 migraineurs with 6912 attacks randomly assigned to 14 different drugs. The data of ketorolac and prochlorperazine were missing. We found that sumatriptan nasal spray and zolmitriptan nasal spray were superior to placebo in the two efficacy outcomes, whereas almotriptan, rizatriptan, sumatriptan with naproxen sodium, ibuprofen and ibuprofen suspension were superior to placebo only in one of the efficacy outcomes. And in network meta-analysis, we found the best 3 treatments were ibuprofen, sumatriptan with naproxen sodium and ibuprofen suspension in achieving pain-free. Meanwhile, the best 3 treatments were ibuprofen suspension, ibuprofen, and rizatriptan in achieving pain relief. In conclusion, in acute treatments of pediatric migraine, most triptans and NSAIDS were effective to achieve pain-free or pain-relief. And the most effective treatment to achieve pain-free is sumatriptan with naproxen sodium. Ibuprofen and ibuprofen suspension were the most effective treatments to achieve painrelief.
机构:
Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, ItalyUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Cipriani, Andrea
Barbui, Corrado
论文数: 0引用数: 0
h-index: 0
机构:Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Barbui, Corrado
Salanti, Georgia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, GreeceUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Salanti, Georgia
Rendell, Jennifer
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Rendell, Jennifer
Brown, Rachel
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Brown, Rachel
Stockton, Sarah
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Stockton, Sarah
Purgato, Marianna
论文数: 0引用数: 0
h-index: 0
机构:Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Purgato, Marianna
Spineli, Loukia M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, GreeceUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Spineli, Loukia M.
Goodwin, Guy M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Goodwin, Guy M.
Geddes, John R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Dias, S.
Welton, N. J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Welton, N. J.
Caldwell, D. M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Psychiat, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Caldwell, D. M.
Ades, A. E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
机构:
Mayo Clin, Dept Neurol, Phoenix, AZ USAUniv Hosp Essen, Dept Neurol, Essen, Germany
Dodick, David W.
Silberstein, Stephen D.
论文数: 0引用数: 0
h-index: 0
机构:
Thomas Jefferson Univ, Jefferson Headache Ctr, Philadelphia, PA 19107 USAUniv Hosp Essen, Dept Neurol, Essen, Germany
Silberstein, Stephen D.
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Albert Einstein Coll Med, Dept Neurol, Montefiore Headache Ctr, Bronx, NY 10467 USA
Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USAUniv Hosp Essen, Dept Neurol, Essen, Germany
机构:
Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, ItalyUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Cipriani, Andrea
Barbui, Corrado
论文数: 0引用数: 0
h-index: 0
机构:Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Barbui, Corrado
Salanti, Georgia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, GreeceUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Salanti, Georgia
Rendell, Jennifer
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Rendell, Jennifer
Brown, Rachel
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Brown, Rachel
Stockton, Sarah
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Stockton, Sarah
Purgato, Marianna
论文数: 0引用数: 0
h-index: 0
机构:Univ Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Purgato, Marianna
Spineli, Loukia M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, GreeceUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Spineli, Loukia M.
Goodwin, Guy M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
Goodwin, Guy M.
Geddes, John R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oxford, Dept Psychiat, Oxford, EnglandUniv Verona, WHO Collaborating Ctr Res & Training Mental Hlth, Dept Publ Hlth & Community Med,Policlin G B Rossi, Dept Med & Publ Hlth,Sect Psychiat & Clin Psychol, I-37134 Verona, Italy
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Dias, S.
Welton, N. J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Welton, N. J.
Caldwell, D. M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Psychiat, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
Caldwell, D. M.
Ades, A. E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, EnglandUniv Bristol, Acad Unit Primary Care, Dept Community Based Med, Bristol BS6 6JL, Avon, England
机构:
Mayo Clin, Dept Neurol, Phoenix, AZ USAUniv Hosp Essen, Dept Neurol, Essen, Germany
Dodick, David W.
Silberstein, Stephen D.
论文数: 0引用数: 0
h-index: 0
机构:
Thomas Jefferson Univ, Jefferson Headache Ctr, Philadelphia, PA 19107 USAUniv Hosp Essen, Dept Neurol, Essen, Germany
Silberstein, Stephen D.
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Albert Einstein Coll Med, Dept Neurol, Montefiore Headache Ctr, Bronx, NY 10467 USA
Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USAUniv Hosp Essen, Dept Neurol, Essen, Germany