Cloning and sequence analysis of an intron-containing domain from a peptide synthetase-encoding gene of the entomopathogenic fungus Metarhizium anisopliae
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作者:
Bailey, AM
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Bailey, AM
Kershaw, MJ
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Kershaw, MJ
Hunt, BA
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Hunt, BA
Paterson, IC
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Paterson, IC
Charnley, AK
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Charnley, AK
Reynolds, SE
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Reynolds, SE
Clarkson, JM
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机构:Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
Clarkson, JM
机构:
[1] Microbial Pathogenicity Group, School of Biology and Biochemistry, University of Bath
[2] School of Biology and Biochemistry, University of Bath, Bath BA2 7AY, Claverton Down
A gene encoding a putative peptide synthetase has been cloned and partially sequenced from the filamentous fungus, Metarhizium anisopliae. The deduced amino acid sequence of one entire domain and the following spacer is typical of fungal peptide synthetases, showing good conservation of the six expected core sequences. There are two introns within this region, the first interrupting core 5 (RLDLTDIE) of the domain and the second in a conserved area of the spacer region.