Co-infection in Children With Bloody Diarrhea Caused by Shiga Toxin-Producing Escherichio coli: Data of the North Italian HUS Network

被引:10
|
作者
Ardissino, Gianluigi [1 ]
Possenti, Ilaria [1 ]
Salardi, Stefania [1 ]
Tel, Francesca [1 ]
Colombo, Elisa [1 ]
Testa, Sara [1 ]
Daprai, Laura [2 ]
Picicco, Damiano [2 ]
Colombo, Rosaria Maria [2 ]
Torresani, Erminio [2 ]
机构
[1] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Ctr HUS Prevent Control & Management, I-20122 Milan, Italy
[2] Osped Maggiore Policlin, Fdn IRCCS Ca Granda, Unit Microbiol, I-20122 Milan, Italy
来源
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 2014年 / 59卷 / 02期
关键词
bloody diarrhea; co-infection; Shiga toxin-producing Escherichia coli; HEMOLYTIC-UREMIC SYNDROME; CAMPYLOBACTER-JEJUNI;
D O I
10.1097/MPG.0000000000000420
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hemolytic-uremic syndrome (HUS) is an important cause. of acute kidney injury in children often caused by Shiga toxin producing Escherichia coli (STEC) enterocolitis. In a screening program for STEC infection in children with bloody diarrhea in northern Italy for early diagnosis of HUS, co-infection with Salmonella or Campylobacter was documented in as many as 35.6% of Shiga toxin positive patients. It is speculated that infection by Salmonella or Campylobacter may increase the risk of STEC enterocolitis and therefore of HUS. The isolation of microorganisms (other then STEC) in HUS should not be necessarily regarded as the etiological agent for the thrombotic microangiopathy.
引用
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页码:218 / 220
页数:3
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