Dielectric Properties of the Human Red Blood Cell

被引:4
作者
Generalov, V. M. [1 ]
Safatov, A. S. [1 ]
Kruchinina, M. V. [2 ]
Gromov, A. A. [2 ]
Buryak, G. A. [1 ]
Generalov, K. V. [1 ]
Kruchinin, V. N. [3 ]
机构
[1] State Res Ctr Virol & Biotechnol Vector, Fed Serv Surveillance Consumer Rights Protect & H, Koltsov, Novosibirsk Reg, Russia
[2] Russian Acad Sci, Res Inst Internal & Prevent Med, Branch Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia
[3] Russian Acad Sci, Siberian Branch, Rzhanov Inst Semicond Phys, Novosibirsk, Russia
基金
俄罗斯基础研究基金会;
关键词
erythrocyte; dielectric constant; electrical capacitance; dielectric loss tangent; dielectrophoresis; ERYTHROCYTE-MEMBRANES;
D O I
10.1007/s11018-020-01826-9
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The dielectric properties of the erythrocyte were studied. Experimental methods and results of measuring the dielectric properties of individual human erythrocyte are presented. The method is theoretically justified. It is found that values of the complex permittivity of the erythrocyte, electrical capacitance, dielectric loss tangent remain almost constant despite significant changes in conductivity and the content of NaCl in the cell suspension. These values reflect the stability of the studied parameters of erythrocytes under conditions of changes within a wide range of the environment in which the cells are located. Complex cell permittivity and cell dielectric loss tangent are promising parameters for objective diagnostics of human diseases. The introduction of measurements of cell permittivity and cell dielectric loss tangent into medical practice will likely allow us to characterize the process of individual cell self-regulation in more detail.
引用
收藏
页码:580 / 586
页数:7
相关论文
共 18 条
  • [1] Akhadov Y. Y., 1972, DIELECTRIC PROPERTIE
  • [2] [Anonymous], 2011, DIELECTROPHORESIS DI
  • [3] Bilirubin induces loss of membrane lipids and exposure of phosphatidylserine in human erythrocytes
    Brito, MA
    Silva, RFM
    Brites, D
    [J]. CELL BIOLOGY AND TOXICOLOGY, 2002, 18 (03) : 181 - 192
  • [4] ELECTROPHORETIC STUDY OF CELL-SURFACE PROPERTIES THEORY AND EXPERIMENTAL APPLICABILITY
    DONATH, E
    PASTUSHENKO, V
    [J]. BIOELECTROCHEMISTRY AND BIOENERGETICS, 1980, 7 (01): : 31 - 40
  • [5] VISCOELASTIC PROPERTIES OF ERYTHROCYTE-MEMBRANES IN HIGH-FREQUENCY ELECTRIC-FIELDS
    ENGELHARDT, H
    GAUB, H
    SACKMANN, E
    [J]. NATURE, 1984, 307 (5949) : 378 - 380
  • [6] Dielectrophoretic detection of changes in erythrocyte membranes following malarial infection
    Gascoyne, P
    Pethig, R
    Satayavivad, J
    Becker, FF
    Ruchirawat, M
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1997, 1323 (02): : 240 - 252
  • [7] DIELECTRIC-SPECTROSCOPY OF HUMAN ERYTHROCYTES - INVESTIGATIONS UNDER THE INFLUENCE OF NYSTATIN
    GIMSA, J
    SCHNELLE, T
    ZECHEL, G
    GLASER, R
    [J]. BIOPHYSICAL JOURNAL, 1994, 66 (04) : 1244 - 1253
  • [8] Gopala KG, 1989, J BIOMED ENG, V11, P375, DOI [10.1016/0141-5425(89)90099, DOI 10.1016/0141-5425(89)90099]
  • [9] Hughes M.P., 2003, NANOELECTROMECHANICS
  • [10] Measuring the dielectric properties of herpes simplex virus type 1 virions with dielectrophoresis
    Hughes, MP
    Morgan, H
    Rixon, FJ
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2002, 1571 (01): : 1 - 8