Acute Lymphoid Leukemia After Anti-TNF-alpha Treatment: A Case Report and Review of the Literature

被引:0
作者
Gediz Ozdemirkiran, Fusun [1 ]
Payzin, Bahriye Kadriye [1 ]
Coban, Eyup [2 ]
Bayram, Korhan Baris [3 ]
Kucukzeybek, Betul [4 ]
机构
[1] Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Hematol, TR-35360 Izmir, Turkey
[2] Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Internal Med, TR-35360 Izmir, Turkey
[3] Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Phys Med & Rehabil, TR-35360 Izmir, Turkey
[4] Katip Celebi Univ, Ataturk Training & Res Hosp, Dept Pathol, TR-35360 Izmir, Turkey
关键词
Acute lymphoid leukemia; ankylosing spondylitis; anti-tumor necrosis factor-alpha drugs; PATIENT RECEIVING ETANERCEPT; NECROSIS-FACTOR INHIBITORS; ACUTE MYELOGENOUS LEUKEMIA; ACUTE MYELOID-LEUKEMIA; RHEUMATOID-ARTHRITIS; MALIGNANCIES; THERAPY; RISK; ADALIMUMAB; INFLIXIMAB;
D O I
10.5606/ArchRheumatol.2015.5669
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The efficacy and safety of anti-tumor necrosis factor-alpha drugs have been shown in active ankylosing spondylitis cases that are resistant to traditional disease-modifying antirheumatic drugs. However, it is well known that these drugs may cause some complications as reactivation of tuberculosis and various hematologic malignancies. In this article, we report a 40-year-old male patient with ankylosing spondylitis who developed Philadelphia chromosome-positive acute lymphoid leukemia after treatment with tumor necrosis factor-alpha inhibitors.
引用
收藏
页码:349 / 352
页数:4
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