An unexpected copper(II)-catalyzed three-component reaction of quinazoline 3-oxide, alkylidenecyclopropane, and water

被引：13
作者：
An, Yuanyuan [1 ]
Zheng, Danqing [1 ]
Wu, Jie [1 ,2 ]
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 65期
基金：
中国国家自然科学基金;
关键词：
UNIQUE TETRASUBSTITUTED ALKENE; DIVERSITY-ORIENTED SYNTHESIS; TRIFLATE-CATALYZED REACTION; ORGANIC-SYNTHESIS; MOLECULAR COMPLEXITY; LEWIS; CYCLIZATION; METHYLENECYCLOPROPANES; BICYCLOPROPYLIDENE; CYCLOADDITION;
D O I：
10.1039/c4cc04341c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An unexpected copper(II)-catalyzed three-component reaction of quinazoline-3-oxide, alkylidenecyclopropane and water under mild conditions is reported. This transformation including [3+2] cyclo-addition and intramolecular rearrangement leads to N-(2-(5-oxa-6-azaspiro[2.4]hept-6-en-7-yl)phenyl)formamides in good yields.
引用
收藏
页码：9165 / 9167
页数：3
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