Approaching the mechanism of protein transport across the ER membrane

被引：67
作者：
Rapoport, TA
Rolls, MM
Jungnickel, B
机构：
[1] Harvard University, Harvard Medical School, Dept. of Cell Biology, Boston, MA 02115
来源：
CURRENT OPINION IN CELL BIOLOGY | 1996年 / 8卷 / 04期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0955-0674(96)80027-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Since the identification of essential protein-translocation components in the endoplasmic reticulum membrane, research efforts have concentrated on the elucidation of the molecular mechanism of protein transport across this membrane. Recent results have provided new information as to how proteins are targeted to, and inserted into, the translocation site during translation. Post-translational translocation has also been examined and is distinct from cotranslational translocation with respect to the mechanism and membrane protein components involved.
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收藏
页码：499 / 504
页数：6
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