Phyllodes Tumor as a Secondary Neoplasm in Survivors of Childhood Cancer: A Tertiary Care Cancer Centre Experience

被引:0
作者
Agrawal, Radhika [1 ]
Sahay, Ayushi [1 ]
Patil, Asawari [1 ]
Ramadwar, Mukta [1 ]
Prasad, Maya [2 ]
Popat, Palak [3 ]
Joshi, Shalaka [4 ]
Shet, Tanuja [1 ]
Desai, Sangeeta [1 ]
机构
[1] Homi Bhabha Natl Inst HBNI, Dept Pathol, Tata Mem Ctr, 8th Floor,Annex Bldg, Mumbai 400012, Maharashtra, India
[2] Homi Bhabha Natl Inst HBNI, Dept Pediat Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India
[3] Homi Bhabha Natl Inst HBNI, Dept Radiol, Tata Mem Ctr, Mumbai, Maharashtra, India
[4] Homi Bhabha Natl Inst HBNI, Dept Surg Oncol, Tata Mem Ctr, Mumbai, Maharashtra, India
关键词
phyllodes tumor; secondary neoplasm; childhood cancer survivor; Li-Fraumeni syndrome; BREAST-CANCER;
D O I
10.1097/MPH.0000000000002415
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Secondary neoplasms (SNs) are being increasingly identified in long-term survivors of childhood cancer. Phyllodes tumor (PT) form a distinctly uncommon SN. We report a series of 6 female childhood cancer survivors who developed PT as SN. The median age at primary diagnosis was 13 years. Their primary tumors were bone sarcoma (4) and acute leukemia (2), and all were treated with chemotherapy, predominantly with alkylating agents and/or anthracyclines. None had received direct radiotherapy to the chest wall. Subsequently, PT were detected after a median interval of 7.5 years, with 2 patients developing bilateral and malignant PT. The series highlights a rare SN in childhood cancer survivors, underscoring the importance of regular long-term follow-up.
引用
收藏
页码:264 / 267
页数:4
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