An expedient synthesis of novel bis[thienopyridines] linked to arene or heteroarene core as novel hybrid molecules

A series of novel bis(thieno[2,3-b]pyridines) based arenes or heteroarenes have been synthesized from the appropriate bis-bromoacetyl derivatives upon treatment with the corresponding 2-mercaptonicotinonitrile derivatives in ethanolic sodium ethoxide at reflux. Attempts to synthesize these compounds via bis-alkylation of the appropriate phenol derivative with the corresponding dibromo compounds using a mild base were unsuccessful. [GRAPHICS] .