Pediatric lung transplantation: supply and demand

被引:12
作者
Benoit, Tobias M. [1 ]
Benden, Christian [2 ]
机构
[1] Univ Hosp Zurich, Div Internal Med, Zurich, Switzerland
[2] Univ Hosp Zurich, Div Pulm Med, Zurich, Switzerland
关键词
children; chronic allograft dysfunction; extracorporeal membrane oxygenation; lung transplantation; pediatric; transition; INTERNATIONAL SOCIETY; IMMUNOSUPPRESSIVE AGENTS; OUTCOMES; HEART; CHILDREN; INFECTIONS; GUIDELINES; MANAGEMENT; RECIPIENTS; SUPPORT;
D O I
10.1097/MOT.0000000000000630
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
Purpose of review Lung transplantation has become an accepted therapy in infants, children, and adolescents suffering from end-stage lung diseases, an impaired quality of life and reduced life expectancy. The aim of this review is to highlight specific aspects of pediatric lung transplantation and to give an update on recent findings. Recent findings Currently, over 100 lung transplant procedures are performed in children annually worldwide. Long-term success is limited by availability of donor organs and waitlist mortality pretransplant, and an increased infection risk because of immunosuppression, and most importantly late complications, such as chronic lung allograft dysfunction, medication nonadherence, and transition intricacies. Summary Specific aspects of pediatric lung transplantation will be reviewed and an update on most recent developments in the management of pediatric lung transplant recipients given.
引用
收藏
页码:324 / 328
页数:5
相关论文
共 44 条
[1]   Extracorporeal Life Support in Lung Transplantation [J].
Abrams, Darryl ;
Brodie, Daniel ;
Arcasoy, Selim M. .
CLINICS IN CHEST MEDICINE, 2017, 38 (04) :655-+
[2]   Indications for lung resection surgery and lung transplant in South American children with cystic fibrosis [J].
Adde, Fabiola Villac ;
Campos, Silvia Vidal ;
de Oliveira Braga Teixeira, Ricardo Henrique ;
Rodrigues, Joaquim Carlos .
PAEDIATRIC RESPIRATORY REVIEWS, 2018, 25 :37-42
[3]  
AMMERMAN E, 2017, PEDIATR TRANSPLANT, V31
[4]   Variability in immunization guidelines in children before and after lung transplantation [J].
Benden, Christian ;
Danziger-Isakov, Lara A. ;
Astor, Todd ;
Aurora, Paul ;
Bluemchen, Katharina ;
Boyer, Debra ;
Conrad, Carol ;
Eichler, Irmgard ;
Elidemir, Okan ;
Goldfarb, Samuel ;
Michaels, Marian G. ;
Mogayzel, Peter J. ;
Mueller, Carsten ;
Parakininkas, Daiva ;
Oberkfell, Donna ;
Solomon, Melinda ;
Boehler, Annette .
PEDIATRIC TRANSPLANTATION, 2007, 11 (08) :882-887
[5]   Pediatric lung transplantation [J].
Benden, Christian .
JOURNAL OF THORACIC DISEASE, 2017, 9 (08) :2675-2683
[6]   Therapy options for chronic lung allograft dysfunction-bronchiolitis obliterans syndrome following first-line immunosuppressive strategies: A systematic review [J].
Benden, Christian ;
Haughton, Maria ;
Leonard, Saoirse ;
Huber, Lars C. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2017, 36 (09) :921-933
[7]   New Developments In Treatment After Lung Transplantation [J].
Benden, Christian ;
Danziger-Isakov, Lara ;
Faro, Albert .
CURRENT PHARMACEUTICAL DESIGN, 2012, 18 (05) :737-746
[8]   Size-reduced lung transplantation in children - an option worth to consider! [J].
Benden, Christian ;
Inci, Ilhan ;
Weder, Walter ;
Boehler, Annette .
PEDIATRIC TRANSPLANTATION, 2010, 14 (04) :529-533
[9]   New immunosuppressive agents in pediatric transplantation [J].
Christina Nguyen ;
Shapiro, Ron .
CLINICS, 2014, 69 :8-16
[10]   Current status of immunosuppressive agents for solid organ transplantation in children [J].
Coelho, Tracy ;
Tredger, Michael ;
Dhawan, Anil .
PEDIATRIC TRANSPLANTATION, 2012, 16 (02) :106-122