Application of phenylphosphate mimetics to the design and synthesis of olefin metathesis-derived Grb2 SH2 domain-binding macrocycles

被引：0
|
作者：
Kang, Sang-Uk [1 ]
Shi, Zhen-Dan [1 ]
Kariki, Rajeshri [1 ]
Phan, Jason [2 ]
Worthy, Karen M. [3 ]
Bindu, Lakshman K. [3 ]
Nicklaus, Marc [1 ]
Waugh, David S. [2 ]
Fisher, Robert J. [3 ]
Burke, Terrence R., Jr. [1 ]
机构：
[1] NCI, Med Chem Lab, NIH, Ft Detrick, MD 21702 USA
[2] NCI, NIH, Macromol Crystllog Lab, CCR, Frederick, MD 21702 USA
[3] Prot Chem Lab, SAIC Frederick, Frederick, MD 21702 USA
来源：
UNDERSTANDING BIOLOGY USING PEPTIDES | 2006年
关键词：
D O I：
10.1007/978-0-387-26575-9_74
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：180 / +
页数：2
相关论文
共 50 条
  • [41] Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles
    Oishi, S
    Shi, ZD
    Worthy, KM
    Bindu, LK
    Fisher, RJ
    Burke, TR
    CHEMBIOCHEM, 2005, 6 (04) : 668 - 674
  • [42] Development of a phosphatase-stable phosphotyrosyl mimetic suitably protected for the synthesis of high-affinity Grb2 SH2 domain-binding ligands
    Wei, CQ
    Li, BH
    Guo, RB
    Yang, DJ
    Burke, TR
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (19) : 2781 - 2784
  • [43] Development of binding assays for the SH2 domain of Grb7 and Grb2 using fluorescence polarization
    Luzy, Jean-Philippe
    Chen, Huixiong
    Gril, Brunilde
    Liu, Wang-Qing
    Vidal, Michel
    Perdereau, Dominique
    Burnol, Anne-Franicoise
    Garbay, Christiane
    JOURNAL OF BIOMOLECULAR SCREENING, 2008, 13 (02) : 112 - 119
  • [44] Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2
    Ettmayer, P
    France, D
    Gounarides, J
    Jarosinski, M
    Martin, MS
    Rondeau, JM
    Sabio, M
    Topiol, S
    Weidmann, B
    Zurini, M
    Bair, KW
    JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (06) : 971 - 980
  • [45] Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic
    Oishi, S
    Karki, RG
    Shi, ZD
    Worthy, KM
    Bindu, L
    Chertov, O
    Esposito, D
    Frank, P
    Gillette, WK
    Maderia, M
    Hartley, J
    Nicklaus, MC
    Barchi, JJ
    Fisher, RJ
    Burke, TR
    BIOORGANIC & MEDICINAL CHEMISTRY, 2005, 13 (07) : 2431 - 2438
  • [46] Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2
    Xu, XX
    Yi, TL
    Tang, B
    Lambeth, JD
    ONCOGENE, 1998, 16 (12) : 1561 - 1569
  • [47] Design and synthesis of triazole-containing macrocylclic tetrapeptide as novel Grb2 SH2 domain ligands
    Shi, Zhen-Dan
    Worthy, Karen M.
    Fisher, Robert J.
    Burke, Terrence R., Jr.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [48] Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2
    Xiang-Xi Xu
    Taolin Yi
    Bo Tang
    J David Lambeth
    Oncogene, 1998, 16 : 1561 - 1569
  • [49] Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems
    Noguchi, Taro
    Ishiba, Hiroyuki
    Honda, Kaori
    Kondoh, Yasumitsu
    Osada, Hiroyuki
    Ohno, Hiroaki
    Fujii, Nobutaka
    Oishi, Shinya
    BIOCONJUGATE CHEMISTRY, 2017, 28 (02) : 609 - 619
  • [50] Macrocyclization in the design of non phosphorus-containing GRB2 SH2 domain-binding ligands that exhibit high affinity in cell-based assays.
    Shi, ZD
    Wei, CQ
    Gao, Y
    Lee, K
    Vasselli, J
    Zhang, MC
    Liu, HP
    Yang, DJ
    Linehan, M
    Burke, TR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U174 - U174
12345