Update Hygiene: Prevention of Vascular Catheter-Associated Infections in Premature and Newborn Infants

Background In May 2018, the commission on infection prevention and control in Germany (KRINKO) of the RKI published a guidance document providing recommendations on the prevention of catheter-associated infections in premature children and newborns. Aim Summarized presentation, explanation and discussion of the KRINKO recommendations. Methods The recommendations of the KRINKO were summarized and discussed with reference to the original sources. Results In particular, statements were formulated for the insertion and maintenance of vascular catheters and for the preparation of infusions. Overall, however, the evidence of the recommendations is low. About 26% (19 out of 74) are classified under category IA or IB. However, 40% of the recommendations are category II only and therefore based on indicative clinical or epidemiological studies or comprehensible theoretical justifications. Accordingly, there is a lack of urgently needed clinical trials. Discussion Prevention strategies were discussed in detail and practical issues were addressed. The high number of recommendations, sometimes with low evidence levels, suggests a shared assessment of the infection control team and clinicians to ensure a successful implementation in practice and a focus on key content adapted to the local situation.