Autologous serum therapy of the ocular surface with novel delivery by platelet concentrate gel

被引：14

作者：

Koffler, Bruce H. ^{[1
]}

机构：

[1] Univ Kentucky, Med Ctr, Dept Ophthalmol, Lexington, KY USA

来源：

OCULAR SURFACE | 2006年 / 4卷 / 04期

关键词：

autologous platelet concentrate gel; autologous serum; epidermal growth factor; neurotrophic keratitis; ocular surface disease; persistent epithelial defect; platelet-rich serum; Sjogren syndrome; transforming growth factor; vitamin A;

D O I：

10.1016/S1542-0124(12)70165-9

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Application of autologous serum to treat a multitude of ocular surface diseases and conditions is a relatively new technique that has gained popularity over the past 10 years. This review focuses on the use of topical autologous serum and a new platelet gel delivery technique that utilizes autologous platelet concentrate mixed with calcium chloride and thrombin for gelling serum, which can then be applied easily to the corneal surface. Residual platelet serum concentrate can be mixed with artificial tears that are capable of gelling in a 25% concentrate, which is then used by the patient postoperatively. A review of the literature identifies various concentrations of autologous serum, frequency of application, and storage criteria.

引用

页码：188 / 195

页数：8

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