Massive Perivillous Fibrin Deposition in Congenital Cytomegalovirus Infection: A Case Report

被引：7

作者：

Gestrich, Catherine K. ^{[1
]}

Zhou, Yi Yuan ^{[1
]}

Ravishankar, Sanjita ^{[1
]}

机构：

[1] Case Western Reserve Univ, Univ Hosp Cleveland, Med Ctr, Dept Pathol, Cleveland, OH 44106 USA

来源：

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY | 2021年 / 24卷 / 01期

关键词：

Cytomegalovirus; placenta; massive perivillous fibrin deposition; MATERNAL FLOOR INFARCTION; ASSOCIATION; PLACENTA;

D O I：

10.1177/1093526620961352

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Cytomegalovirus (CMV) infection is one of the most common congenital viral infections. Classically associated placental findings include chronic villitis with plasma cells, stromal hemosiderin deposition, and identification of viral inclusions in villous endothelial and stromal cells. We present a case of confirmed congenital CMV infection that lacked these classical findings, but demonstrated massive perivillous fibrin deposition (MPVFD). This is the first report of CMV associated with MPVFD. MPVFD is an uncommon placental lesion associated with adverse fetal outcomes and a high risk of recurrence. However, the recurrence risk in patients with an infectious cause may be lower in than patients with other associated clinical conditions.

引用

页码：47 / 50

页数：4

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